Characteristics of subtype III-A CRISPR-Cas system in Mycobacterium tuberculosis: An overview

被引：4
|
作者：
Hamdi, Insaf [1 ]
Boni, Funmilayo [1 ]
Shen, Qinglei [1 ]
Moukendza, Liadrine [1 ]
Peibo, Li [2 ]
Jianping, Xie [1 ,2 ]
机构：
[1] Southwest Univ, Inst Modern Biopharmaceut,Sch Life Sci, State Key Lab Breeding Base Ecoenvironm & Bioreso, Key Lab Ecoenvironm Three Gorges Reservoir Reg,Min, Chongqing 400715, Peoples R China
[2] Southwest Univ, Publ Hlth Hosp, Chongqing Publ Hlth Med Ctr, Chongqing 400030, Peoples R China
来源：
INFECTION GENETICS AND EVOLUTION | 2023年 / 112卷
关键词：
Mycobacterium tuberculosis; CRISPR-Cas III-A; Reverse transcriptase (RT); Housekeeping nuclease-anti-CRISPR; CRISPRi; COMPLEX; RNA; BACTERIA; CLASSIFICATION; MECHANISMS; KNOCKDOWN; INSIGHTS; ROLES;
D O I：
10.1016/j.meegid.2023.105445
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
CRISPR-Cas systems are the only RNA- guided adaptive immunity pathways that trigger the detection and destruction of invasive phages and plasmids in bacteria and archaea. Due to its prevalence and mystery, the Class 1 CRISPR-Cas system has lately been the subject of several studies. This review highlights the specificity of CRISPR-Cas system III-A in Mycobacterium tuberculosis, the tuberculosis-causing pathogen, for over twenty years. We discuss the difference between the several subtypes of Type III and their defence mechanisms. The antiCRISPRs (Acrs) recently described, the critical role of Reverse transcriptase (RT) and housekeeping nuclease for type III CRISPR-Cas systems, and the use of this cutting-edge technology, its impact on the search for novel anti-tuberculosis drugs.
引用
收藏
页数：11
相关论文
共 50 条
  • [41] The ribonuclease activity of Csm6 is required for anti-plasmid immunity by Type III-A CRISPR-Cas systems
    Foster, Kawanda
    Kalter, Joshua
    Woodside, Walter
    Terns, Rebecca M.
    Terns, Michael P.
    RNA BIOLOGY, 2019, 16 (04) : 449 - 460
  • [42] A new method for the detection of Mycobacterium tuberculosis based on the CRISPR/Cas system
    Xiaoyu Zhang
    Xiaoying He
    Yubo Zhang
    Lei Chen
    Zhaobao Pan
    Yueying Huang
    Heng Li
    BMC Infectious Diseases, 23
  • [43] A new method for the detection of Mycobacterium tuberculosis based on the CRISPR/Cas system
    Zhang, Xiaoyu
    He, Xiaoying
    Zhang, Yubo
    Chen, Lei
    Pan, Zhaobao
    Huang, Yueying
    Li, Heng
    BMC INFECTIOUS DISEASES, 2023, 23 (01)
  • [44] Potential of the CRISPR-Cas system for improved parasite diagnosis CRISPR-Cas mediated diagnosis in parasitic infections
    You, Hong
    Gordon, Catherine A.
    MacGregor, Skye R.
    Cai, Pengfei
    McManus, Donald P.
    BIOESSAYS, 2022, 44 (04)
  • [45] The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system
    Behler, Juliane
    Sharma, Kundan
    Reimann, Viktoria
    Wilde, Annegret
    Urlaub, Henning
    Hess, Wolfgang R.
    NATURE MICROBIOLOGY, 2018, 3 (03): : 367 - 377
  • [46] The structural biology of type III CRISPR-Cas systems
    Li, Xuzichao
    Han, Jie
    Yang, Jie
    Zhang, Heng
    JOURNAL OF STRUCTURAL BIOLOGY, 2024, 216 (01)
  • [47] In vitro assembly of thermostable Csm complex in CRISPR-Cas type III/A system
    Park, Kwang-Hyun
    An, Yan
    Woo, Eui-Jeon
    CRISPR-CAS ENZYMES, 2019, 616 : 173 - 189
  • [48] The Application of the CRISPR-Cas System in Antibiotic Resistance
    Tao, Shuan
    Chen, Huimin
    Li, Na
    Liang, Wei
    INFECTION AND DRUG RESISTANCE, 2022, 15 : 4155 - 4168
  • [49] CRISPR-Cas System for RNA Detection and Imaging
    Chen Siyu
    Wang Rujia
    Lei Chunyang
    Nie Zhou
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2020, 36 (02) : 157 - 163
  • [50] Lamarckian realities: the CRISPR-Cas system and beyond
    Jablonka, Eva
    BIOLOGY & PHILOSOPHY, 2019, 34 (01)
12345