Identification of novel inhibitors targeting KRAS-SOS1 interactions by structure-based drug design

被引:0
|
作者
Patel, Neel A. [1 ]
Hasse, Timothy [1 ]
Malin, Evan [1 ]
Kelm, Jeremy M. [1 ]
Gavande, Navnath [1 ]
Huang, Yu-Ming [1 ]
机构
[1] Wayne State Univ, Detroit, MI USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
897-Pos
引用
收藏
页码:184A / 184A
页数:1
相关论文
共 50 条
  • [31] Structure-based drug design of macrocyclic factor XIa inhibitors
    Corte, James
    Fang, Tianan
    Osuna, Honey
    Pinto, Donald
    Rossi, Karen
    Rendina, Alan
    Bozarth, Jeffrey
    Sheriff, Steven
    Myers, Joseph
    Harper, Timothy
    Lou, Zhen
    Zheng, Joanna
    Luettgen, Joseph
    Seiffert, Dietmar
    Lam, Patrick
    Wexler, Ruth
    Quan, Mimi
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [32] Structure-based drug design of HIV protease inhibitors.
    Navia, MA
    Tung, RD
    Chaturvedi, PR
    Rao, BG
    Partaledis, JA
    Kim, EE
    FASEB JOURNAL, 1996, 10 (06): : 2436 - 2436
  • [33] Structure-based drug design of TRAF6 inhibitors
    Peng, Zhenghong
    Maxwell, David S.
    Sun, Duoli
    Darnay, Bryant G.
    Bornmann, William G.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [34] STRUCTURE-BASED DRUG DESIGN - INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE
    MONTGOMERY, JA
    EALICK, SE
    BABU, S
    BUGG, CE
    ERION, MD
    GUIDA, WC
    SECRIST, JA
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 206 - 206
  • [35] STRUCTURE-BASED DRUG DESIGN - INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE
    MONTGOMERY, JA
    FARMACO, 1993, 48 (02): : 297 - 308
  • [36] Structure-based drug design of selective 5′-nucleotidases inhibitors
    Pachl, P.
    Brynda, J.
    Rosenberg, I.
    Fabry, M.
    Rezacova, P.
    FEBS JOURNAL, 2009, 276 : 159 - 159
  • [37] Structure-based drug design of selective 5'-nucleotidases inhibitors
    Pachl, Petr
    Brynda, Jiri
    Rosenberg, Ivan
    Fabry, Milan
    Rezacova, Pavlina
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2011, 67 : C227 - C228
  • [38] Structure-based design of novel human Pin1 inhibitors (I)
    Guo, Chuangxing
    Hou, Xinjun
    Dong, Liming
    Dagostino, Eleanor
    Greasley, Samantha
    Ferre, RoseAnn
    Marakovits, Joseph
    Johnson, M. Catherine
    Matthews, David
    Mroczkowski, Barbara
    Parge, Hans
    VanArsdale, Todd
    Popoff, Ian
    Piraino, Joseph
    Margosiak, Stephen
    Thomson, James
    Los, Gerrit
    Murray, Brion W.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (19) : 5613 - 5616
  • [39] Structure-Based Design of Novel Benzimidazole Derivatives as Pin1 Inhibitors
    Wang, Shuxiang
    Guan, Lihong
    Zang, Jie
    Xing, Kun
    Zhang, Jian
    Liu, Dan
    Zhao, Linxiang
    MOLECULES, 2019, 24 (07)
  • [40] Structure-based design of novel human Pin1 inhibitors (II)
    Dong, Liming
    Marakovits, Joseph
    Hou, Xinjun
    Guo, Chuangxing
    Greasley, Samantha
    Dagostino, Eleanor
    Ferre, RoseAnn
    Johnson, M. Catherine
    Kraynov, Eugenia
    Thomson, James
    Pathak, Ved
    Murray, Brion W.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (07) : 2210 - 2214