Transcriptomic signatures of MSI-high metastatic colorectal cancer to predict efficacy of immune checkpoint inhibitors

被引：0
|
作者：
Gallois, Claire
Landi, Matteo
Taieb, Julien
Lonardi, Sara
Bergamo, Francesca
Intini, Rossana
Maddalena, Giulia
Pietrantonio, Filippo
Corti, Francesca
Ambrosini, Margherita
Martinetti, Antonia
Germani, Marco Maria
Boccaccio, Chiara
Vetere, Guglielmo
Mouillet-Richard, Sophie
de Reynies, Aurelien
Puig, Pierre Laurent
Cremolini, Chiara
机构：
[1] Univ Paris Cite, Inst Canc Paris CARPEM, Digest Oncol Dept, Hop Europeen G Pompiduo, Paris, France
[2] Univ Pisa, Pisa, Italy
[3] Univ Paris, Dept Gastroenterol & Gastrointestinal Oncol, Hop Europeen Georges Pompidou, AP HP, Paris, France
[4] Veneto Inst Oncol IOV IRCCS, Dept Oncol, Padua, Italy
[5] Veneto Inst Oncol IOV IRCCS, Dept Oncol, Med Oncol 1, Padua, Italy
[6] Veneto Inst Oncol IOV IRCCS, Dept Oncol, Med Oncol 1, Padua, Italy
[7] Ist Oncol Veneto IOV IRCCS, Oncol Unit 1, Padua, Italy
[8] Fdn IRCCS Ist Nazl Tumori, Med Oncol Dept, Milan, Italy
[9] IRCCS Fdn Natl Canc Inst, Milan, Italy
[10] Univ Pisa, Dept Translat Res & New Technol Med & Surg, Pisa, Italy
[11] Azienda Osped Univ Pisana, Unit Med Oncol 2, Pisa, Italy
[12] Univ Paris Cite, Sorbonne Univ, Ctr Rech Cordeliers, INSERM, Paris, France
[13] Inst Canc Paris CARPEM, Dept Biol, Hop Europeen Georges Pompidou, APHP Ctr, Paris, France
[14] Univ Pisa, Dept Translat Res & New Technol Med & Surg, Pisa, Italy
[15] Azienda Osped Univ Pisana, Unit Med Oncol 2, Pisa, Italy
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2023年 / 41卷 / 16期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3570
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Immune Checkpoint Inhibitors in pMMR Metastatic Colorectal Cancer: A Tough Challenge
    Marmorino, Federica
    Boccaccino, Alessandra
    Germani, Marco Maria
    Falcone, Alfredo
    Cremolini, Chiara
    CANCERS, 2020, 12 (08) : 1 - 27
  • [22] Gastrocutaneous Fistula in a Patient with Locally Recurrent MSI-High Colorectal Cancer: Local Complications Arising from Therapeutic Response to Immune Checkpoint Blockade
    Greene, Claire
    Nakakura, Eric K.
    Ko, Andrew H.
    ANTICANCER RESEARCH, 2017, 37 (07) : 3679 - 3684
  • [23] Homologous recombination repair gene mutations predict the efficacy of immune checkpoint inhibitors therapy in colorectal cancer
    Lin, Y.
    Zhang, J.
    Liao, X.
    Zhang, Y.
    Luo, M.
    Li, Q.
    Xie, M.
    Liang, C.
    Liao, S.
    Zheng, Y.
    Hu, X.
    Huang, M.
    Liang, R.
    Li, Y.
    ANNALS OF ONCOLOGY, 2021, 32 : S558 - S558
  • [24] Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer
    Nasca, Vincenzo
    Barretta, Francesco
    Corti, Francesca
    Lonardi, Sara
    Niger, Monica
    Elez, Maria Elena
    Fakih, Marwan
    Jayachandran, Priya
    Shah, Aakash Tushar
    Salati, Massimiliano
    Fenocchio, Elisabetta
    Salvatore, Lisa
    Cremolini, Chiara
    Ros, Javier
    Ambrosini, Margherita
    Mazzoli, Giacomo
    Intini, Rossana
    Overman, Michael J.
    Miceli, Rosalba
    Pietrantonio, Filippo
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (02)
  • [25] Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer
    Nasca, Vincenzo
    Barretta, Francesco
    Corti, Francesca
    Lonardi, Sara
    Niger, Monica
    Elez, Maria Elena
    Fakih, Marwan
    Jayachandran, Priya
    Shah, Aakash Tushar
    Salati, Massimiliano
    Fenocchio, Elisabetta
    Salvatore, Lisa
    Cremolini, Chiara
    Ros, Javier
    Ambrosini, Margherita
    Mazzoli, Giacomo
    Intini, Rossana
    Overman, Michael J.
    Miceli, Rosalba
    Pietrantonio, Filippo
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (01)
  • [26] Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors
    Nunez, Nicolas Gonzalo
    Berner, Fiamma
    Friebel, Ekaterina
    Unger, Susanne
    Wyss, Nina
    Gomez, Julia Martinez
    Purde, Mette-Triin
    Niederer, Rebekka
    Porsch, Maximilian
    Lichtensteiger, Christa
    Kramer, Rafaela
    Erdmann, Michael
    Schmitt, Christina
    Heinzerling, Lucie
    Abdou, Marie-Therese
    Karbach, Julia
    Schadendorf, Dirk
    Zimmer, Lisa
    Ugurel, Selma
    Kluemper, Niklas
    Hoelzel, Michael
    Power, Laura
    Kreutmair, Stefanie
    Capone, Mariaelena
    Madonna, Gabriele
    Cevhertas, Lacin
    Heider, Anja
    Amaral, Teresa
    Ali, Omar Hasan
    Bomze, David
    Dimitriou, Florentia
    Diem, Stefan
    Ascierto, Paolo Antonio
    Dummer, Reinhard
    Jaeger, Elke
    Driessen, Christoph
    Levesque, Mitchell Paul
    van de Veen, Willem
    Joerger, Markus
    Frueh, Martin
    Becher, Burkhard
    Flatz, Lukas
    MED, 2023, 4 (02): : 113 - +
  • [27] Molecular profiling of MSI-high colorectal cancer (CRC) in Indian population
    Naz, Ashmala
    Tourani, Vijaya
    Rao, Satish
    Bashyam, Murali Dharan
    CANCER RESEARCH, 2019, 79 (13)
  • [28] Efficacy and side effects of immune checkpoint inhibitors in the treatment of colorectal cancer
    Manz, Salomon M.
    Losa, Marco
    Fritsch, Ralph
    Scharl, Michael
    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2021, 14
  • [29] Latest evidence on immune checkpoint inhibitors in metastatic colorectal cancer: A 2022 update
    Boukouris, Aristeidis E.
    Theochari, Maria
    Stefanou, Dimitra
    Papalambros, Alexandros
    Felekouras, Evangelos
    Gogas, Helen
    Ziogas, Dimitrios C.
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2022, 173
  • [30] Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
    Xie, Ming-zhi
    Li, Yong-qiang
    Liang, Rong
    Huang, Shi-ying
    Qin, Shan-yu
    Hu, Bang-li
    JOURNAL OF GASTROINTESTINAL CANCER, 2024, 55 (04) : 1620 - 1627
12345