Holmium-doped 58S glass-derived foam-like scaffolds

被引：2
|
作者：
Baino, Francesco [1 ]
Marchi, Juliana [2 ]
Borges, Roger [2 ,3 ]
Verne, Enrica [1 ]
机构：
[1] Politecn Torino, Inst Mat Phys & Engn, Dept Appl Sci & Technol, Corso Duca Abruzzi 24, I-10129 Turin, Italy
[2] Univ Fed ABC, Ctr Ciencias Nat & Humanas, Ave Estados 5001, BR-09210580 Santo Andre, SP, Brazil
[3] Hosp Israelita Albert Einstein, Fac Israelita Ciencias Saude Albert Einstein, Sch Biomed Engn, Sao Paulo, Brazil
来源：
MATERIALS LETTERS | 2023年 / 341卷
基金：
巴西圣保罗研究基金会;
关键词：
Biomaterials; Bioactive glass; Porous materials; Holmium; BIOACTIVE GLASSES; CERAMIC SCAFFOLDS; BIOGLASS;
D O I：
10.1016/j.matlet.2023.134256
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Biocompatible implantable glasses doped with rare earth elements (e.g. holmium) are regarded as promising biomaterials for advanced medical therapies. In this work, Ho-containing scaffolds based on the 58S sol-gel glass composition were fabricated for the first time through sponge replication followed by sinter-crystallization, which was associated to the formation of CaSiO3. The obtained materials exhibited high porosity (86 vol%), trabecular pore-strut 3D architecture and compressive strength (around 1 MPa) comparable to that of osseous tissue, making them promising candidates for use in bone applications.
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页数：3
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