Factors Associated with Spontaneous Preterm Birth after Ultrasound-Indicated Cerclage

被引:1
|
作者
Lee, Kyong-No [1 ]
Yun, Sangho [2 ]
Park, So-Yoon [3 ]
Kim, Kyoungseon [3 ]
Lee, Keun-Young [3 ]
Lee, Jae Jun [2 ,4 ]
Son, Ga-Hyun [2 ,3 ]
机构
[1] Chungnam Natl Univ Hosp, Dept Obstet & Gynecol, Daejeon 35015, South Korea
[2] Hallym Univ, Inst New Frontier Res Team, Coll Med, Chunchon 24252, South Korea
[3] Hallym Univ, Coll Med, Kangnam Sacred Heart Hosp, Div Maternal Fetal Med,Dept Obstet & Gynecol, Seoul 07441, South Korea
[4] Hallym Univ, Coll Med, Dept Anesthesiol & Pain Med, Chunchon 24252, South Korea
来源
JOURNAL OF PERSONALIZED MEDICINE | 2023年 / 13卷 / 12期
关键词
cervical insufficiency; obesity; spontaneous preterm birth; ultrasound-indicated cerclage; BODY-MASS INDEX; UPDATED SYSTEMATIC ANALYSIS; AMNIOTIC-FLUID; EMERGENCY CERCLAGE; UNDER-5; MORTALITY; NATIONAL CAUSES; WEIGHT INFANTS; RISK; OUTCOMES; INSUFFICIENCY;
D O I
10.3390/jpm13121678
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Ultrasound-indicated cerclage (UIC) is recommended to prevent spontaneous preterm birth (sPTB) in women with a short cervix at mid-trimester and a history of PTB. We assessed the factors related to sPTB after UIC and determined the corresponding risks. This retrospective cohort study was conducted at a university hospital. UIC was performed between 15 and 26 weeks of gestation in women with a cervical length of <2.5 cm. Univariate and multivariate analyses were used to examine factors associated with sPTB after UIC. An earlier gestational age and shorter cervical length at UIC were associated with sPTB after UIC. While PTB history was not associated with an increased risk of sPTB, it did increase the risk of repeat cerclage after UIC. Higher levels of preoperative serum inflammatory markers and obesity significantly increased the risk of sPTB after UIC. These findings provide helpful guidance for patient counseling and management in predicting the delivery timing after UIC in women with a short cervix in the mid-trimester.
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页数:10
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