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Birth season and gross brain morphology associated with early neurodevelopment in schizophrenia spectrum patients and healthy subjects
被引:1
|作者:
Takahashi, Tsutomu
[1
,2
,6
]
Sasabayashi, Daiki
[1
,2
]
Takayanagi, Yoichiro
[1
,3
]
Kobayashi, Haruko
[1
,2
]
Torigoe, Misako
[1
,2
]
Sakamoto, Kazumi
[1
]
Yuasa, Yusuke
[1
,2
]
Tsujii, Noa
[4
]
Noguchi, Kyo
[5
]
Suzuki, Michio
[1
,2
]
机构:
[1] Univ Toyama, Grad Sch Med & Pharmaceut Sci, Dept Neuropsychiat, Toyama, Japan
[2] Univ Toyama, Res Ctr Idling Brain Sci, Toyama, Japan
[3] Arisawabashi Hosp, Toyama, Japan
[4] Toyama Univ Hosp, Dept Child Mental Hlth & Dev, Toyama, Japan
[5] Univ Toyama, Grad Sch Med & Pharmaceut Sci, Dept Radiol, Toyama, Japan
[6] Univ Toyama, Grad Sch Med & Pharmaceut Sci, Dept Neuropsychiat, 2630 Sugitani, Toyama 9300194, Japan
关键词:
Magnetic resonance imaging;
Insular cortex;
Gyrification;
OLFACTORY SULCUS;
PREVALENCE;
DEPTH;
D O I:
10.1016/j.pscychresns.2023.111714
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
This MRI study examined the effects of birth seasons on gross brain characteristics, such as the prevalence/size of midline brain structures (cavum septi pellucidi and adhesio interthalamica), orbitofrontal surface morphology, and insular gross anatomy, in 135 patients with schizophrenia, 47 with schizotypal disorder, and 88 healthy controls. Birth seasons only affected the insular anatomy. Summer-born subjects (N = 110) were characterized by more developed left insular gyri than winter-born subjects; however, this effect had no diagnostic specificity. The present results do not support birth seasons affecting the neurodevelopmental pathology of schizophrenia spectrum.
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页数:5
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