Targeting STAT5B in T-cell acute lymphoblastic leukemia

被引：0
|
作者：
Veloso, Alexandra [1 ,2 ]
Cools, Jan [1 ,2 ]
机构：
[1] Katholieke Univ Leuven, Leuven, Belgium
[2] VIB, Leuven, Belgium
来源：
BLOOD | 2023年 / 142卷 / 03期
关键词：
INHIBITION;
D O I：
10.1182/blood.2023020639
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Tremblay et al demonstrate that STAT5B activation drives proliferation, self-renewal, and chemoresistance of leukemia stem cells (LSCs) in an early T-cell precursor acute lymphoblastic leukemia mouse model and explore STAT5B as a direct therapeutic target (see figure).(1)
引用
收藏
页码：215 / 217
页数：3
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