Metal-Free Synthesis of 2-Aminobenzothiazoles via I2-Catalyzed Tandem Cyclization Reaction of Amines and Carbon Disulfide

被引：4

作者：

Chen, Ting ^{[1
]}

Feng, Wei ^{[1
]}

Yang, Ruitong ^{[1
]}

Chen, Shanping ^{[1
]}

Deng, Guo-Jun ^{[1
,2
]}

机构：

[1] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Minist Educ,Key Lab Environm Friendly Chem & Appli, Xiangtan 411105, Hunan, Peoples R China

[2] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Hunan, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2024年 / 42卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Sulfur heterocycles; C-H functionalization; Cyclization; Tandem reaction; Transition-metal-free; Amines; Iodine; N-Heterocycles; RETINOIC ACID METABOLISM; S BOND FORMATION; BIOLOGICAL EVALUATION; C-H; CATALYZED SYNTHESIS; DIRECT AMINATION; AROMATIC-AMINES; COPPER-OXIDE; ONE-POT; INHIBITORS;

D O I：

10.1002/cjoc.202300610

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient approach for the construction of 2-aminobenzothiazoles via I-2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been developed. The present approach starts from simple and readily available starting materials, affording a series of 2-aminobenzothiazoles in up to 89% yields under metal-free conditions. In this work, C-H/N-H functionalization was achieved and multiple C-hetero bonds were successfully constructed in one pot.

引用

页码：846 / 852

页数：7

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