Human Immunodeficiency Virus Type 1 RNA Genital Tract Shedding After Cryotherapy for Cervical Intraepithelial Neoplasia in Western Kenya

被引:0
|
作者
Orang'o, Elkanah Omenge [1 ]
Bocage, Anne E. [2 ]
Liu, Tao D. [3 ]
Itsura, Peter M. [1 ]
Tonui, Philip K. [1 ]
Muthoka, Kapten [4 ]
Stephen, Kiptoo [1 ]
Caliendo, Angela M. [5 ]
Sam, Soya S. [5 ,6 ]
Cu-Uvin, Susan [5 ]
机构
[1] Moi Univ, Dept Reprod Hlth, Eldoret, Kenya
[2] Brown Univ, Warron Alpert Med Sch, 222 Richmond St,Box G-M117, Providence, RI 02912 USA
[3] Brown Univ, Dept Biostat, Providence, RI USA
[4] Acad Model Providing Access Healthcare Partnershi, Eldoret, Kenya
[5] Brown Univ, Div Infect Dis, Warren Alpert Med Sch, Providence, RI 02912 USA
[6] Miriam Hosp, Div Infect Dis, Providence, RI 02906 USA
来源
OPEN FORUM INFECTIOUS DISEASES | 2023年 / 10卷 / 01期
基金
美国国家卫生研究院;
关键词
cervical cancer; cervical cancer treatment; cryotherapy; HIV; HIV genital tract viral load; Kenya; PLASMA; HIV; WOMEN;
D O I
10.1093/ofid/ofac662
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This prospective study of 39 women living with human immunodeficiency virus (HIV) on antiretroviral therapy in Western Kenya aimed to quantify genital tract HIV-1 RNA (GT-HIV RNA) shedding before and after cryotherapy for cervical intraepithelial neoplasia. Most GT-HIV RNA shedding was detected precryotherapy, suggesting that cryotherapy was not the primary cause of shedding.
引用
收藏
页数:5
相关论文
共 50 条
  • [21] Detection and quantitation of human immunodeficiency virus type 1 in the female genital tract
    Baron, P
    Bremer, J
    Wasserman, SS
    Nowicki, M
    Driscoll, B
    Polsky, B
    Kovacs, A
    Reichelderfer, PS
    JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (10) : 3822 - 3824
  • [22] Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV)
    Diem, Kurt
    Nickle, David C.
    Motoshige, Alexis
    Fox, Alan
    Ross, Susan
    Mullins, James I.
    Corey, Lawrence
    Coombs, Robert W.
    Krieger, John N.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 (04) : 561 - 571
  • [23] Association between bacterial vaginosis and expression of human immunodeficiency virus type 1 RNA in the female genital tract
    Cu-Uvin, S
    Hogan, JW
    Caliendo, AM
    Harwell, J
    Mayer, KH
    Carpenter, CCJ
    CLINICAL INFECTIOUS DISEASES, 2001, 33 (06) : 894 - 896
  • [24] Genital human papillomavirus infection and associated penile intraepithelial neoplasia in males infected with the human immunodeficiency virus
    Gomousa-Michael, M
    Gialama, E
    Gomousas, N
    Gialama, G
    ACTA CYTOLOGICA, 2000, 44 (03) : 305 - 309
  • [25] Protease inhibitor monotherapy is effective in controlling human immunodeficiency virus 1 shedding in the male genital tract
    Torres-Cornejo, A.
    BenMarzouk-Hidalgo, O. J.
    Viciana, P.
    Sanchez, B.
    Lopez-Ruz, M. A.
    Lopez-Cortes, L. F.
    Gutierrez-Valencia, A.
    CLINICAL MICROBIOLOGY AND INFECTION, 2016, 22 (01) : 98.e7 - 98.e10
  • [26] Cervical shedding of cytomegalovirus in human immunodeficiency virus type 1-infected women
    Mostad, SB
    Kreiss, JK
    Ryncarz, AJ
    Overbaugh, J
    Mandaliya, K
    Chohan, B
    Ndinya-Achola, J
    Bwayo, JJ
    Corey, L
    JOURNAL OF MEDICAL VIROLOGY, 1999, 59 (04) : 469 - 473
  • [27] CERVICAL INTRAEPITHELIAL NEOPLASIA IN WOMEN INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS - OUTCOME AFTER LOOP ELECTROSURGICAL EXCISION
    WRIGHT, TC
    KOULOS, J
    SCHNOLL, F
    SWANBECK, J
    ELLERBROCK, TV
    CHIASSON, MA
    RICHART, RM
    GYNECOLOGIC ONCOLOGY, 1994, 55 (02) : 253 - 258
  • [28] Human immunodeficiency virus 1 expression in the female genital tract in association with cervical inflammation and ulceration
    Wright, TC
    Subbarao, S
    Ellerbrock, TV
    Lennox, JL
    Evans-Strickfaden, T
    Smith, DG
    Hart, CE
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2001, 184 (03) : 279 - 285
  • [29] Comparison of two amplification technologies for detection and quantitation of human immunodeficiency virus type 1 RNA in the female genital tract
    Bremer, J
    Nowicki, M
    Beckner, S
    Brambilla, D
    Cronin, M
    Herman, S
    Kovacs, A
    Reichelderfer, P
    JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (07) : 2665 - 2669
  • [30] Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: Compartmentalization and intrapatient recombination
    Philpott, S
    Burger, H
    Tsoukas, C
    Foley, B
    Anastos, K
    Kitchen, C
    Weiser, B
    JOURNAL OF VIROLOGY, 2005, 79 (01) : 353 - 363