Progress in the decarboxylative deuteration reaction of alkyl carboxylic acids

被引：2

作者：

Dong, Dao-Qing ^{[1
]}

Yang, Hao ^{[1
]}

Wang, Yan-Li ^{[1
]}

Zhou, Meng-Yu ^{[1
]}

Wei, Ze-Hui ^{[1
]}

Gao, Jia-Hui ^{[1
]}

He, Ling ^{[2
]}

Wang, Zu-Li ^{[1
,3
]}

机构：

[1] Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China

[2] Chongqing Univ, Innovat Drug Res Ctr, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing 401331, Peoples R China

[3] Nanjing Forestry Univ, Natl Engn Res Ctr Low Carbon Proc & Utilizat Fores, Nanjing, Peoples R China

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2024年 / 38卷 / 02期

基金：

中国国家自然科学基金;

关键词：

carboxylic acids; decarboxylation; deuteration; ENZYMATIC-SYNTHESIS; DEUTERIUM; MILD; ISOTOPOMERS; PRECURSORS;

D O I：

10.1002/aoc.7352

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The application of deuterated compounds is increasingly expanding across various fields, making the development of novel deuterium labeling techniques for obtaining deuterated compounds a burgeoning research focus. Carboxylic acids and their derivatives are widely utilized as cost-effective and readily available materials for obtaining deuterated compounds due to their stable properties. This article presents a comprehensive and concise summary of the research progress in decarboxylative deuteration reactions over the past 20 years. The application of deuterated compounds is increasingly expanding across various fields, making the development of novel deuterium labeling techniques for obtaining deuterated compounds a burgeoning research focus. Carboxylic acids and their derivatives are widely utilized as cost-effective and readily available materials for obtaining deuterated compounds due to their stable properties. This article presents a comprehensive and concise summary of the research progress in decarboxylative deuteration reactions over the past 20 years.image

引用

页数：12

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