Progress in the decarboxylative deuteration reaction of alkyl carboxylic acids

被引：2

作者：

Dong, Dao-Qing ^{[1
]}

Yang, Hao ^{[1
]}

Wang, Yan-Li ^{[1
]}

Zhou, Meng-Yu ^{[1
]}

Wei, Ze-Hui ^{[1
]}

Gao, Jia-Hui ^{[1
]}

He, Ling ^{[2
]}

Wang, Zu-Li ^{[1
,3
]}

机构：

[1] Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China

[2] Chongqing Univ, Innovat Drug Res Ctr, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing 401331, Peoples R China

[3] Nanjing Forestry Univ, Natl Engn Res Ctr Low Carbon Proc & Utilizat Fores, Nanjing, Peoples R China

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2024年 / 38卷 / 02期

基金：

中国国家自然科学基金;

关键词：

carboxylic acids; decarboxylation; deuteration; ENZYMATIC-SYNTHESIS; DEUTERIUM; MILD; ISOTOPOMERS; PRECURSORS;

D O I：

10.1002/aoc.7352

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The application of deuterated compounds is increasingly expanding across various fields, making the development of novel deuterium labeling techniques for obtaining deuterated compounds a burgeoning research focus. Carboxylic acids and their derivatives are widely utilized as cost-effective and readily available materials for obtaining deuterated compounds due to their stable properties. This article presents a comprehensive and concise summary of the research progress in decarboxylative deuteration reactions over the past 20 years. The application of deuterated compounds is increasingly expanding across various fields, making the development of novel deuterium labeling techniques for obtaining deuterated compounds a burgeoning research focus. Carboxylic acids and their derivatives are widely utilized as cost-effective and readily available materials for obtaining deuterated compounds due to their stable properties. This article presents a comprehensive and concise summary of the research progress in decarboxylative deuteration reactions over the past 20 years.image

引用

页数：12

共 50 条

[1] A highly selective decarboxylative deuteration of carboxylic acids
Li, Nian
Ning, Yunyun
Wu, Xiaopeng
Xie, Jin
Li, Weipeng
Zhu, Chengjian
CHEMICAL SCIENCE, 2021, 12 (15) : 5505 - 5510
[2] Progress in Photoinduced Decarboxylative Radical Cross-Coupling of Alkyl Carboxylic Acids and Their Derivatives
Zhou, Mingdong
Qin, Pitao
Jing, Like
Sun, Jing
Du, Haiwu
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 40 (03) : 598 - 613
[3] Selective Copper- or Silver-Catalyzed Decarboxylative Deuteration of Aromatic Carboxylic Acids
Rudzki, Martin
Alcalde-Aragones, Ana
Dzik, Wojciech I.
Rodriguez, Nuria
Goossen, Lukas J.
SYNTHESIS-STUTTGART, 2012, 44 (02): : 184 - 193
[4] Catalyst-free decarboxylative deuteration using tailored photoredox-active carboxylic acids
Liu, Shuai
Liao, Hongze
Chen, Bin
Guo, Tengyu
Zhang, Zhizhen
Lin, Houwen
GREEN CHEMISTRY, 2024, 26 (20) : 10456 - 10462
[5] Decarboxylative Acylation of Carboxylic Acids: Reaction Investigation and Mechanistic Study
Wu, Xiaopeng
Han, Jie
Xia, Siyu
Li, Weipeng
Zhu, Chengjian
Xie, Jin
CCS CHEMISTRY, 2022, 4 (07): : 2469 - 2480
[6] Enantioselective decarboxylative protonation and deuteration of β-ketocarboxylic acids
Mizutani, Haruna
Kawanishi, Ryouta
Shibatomi, Kazutaka
CHEMICAL COMMUNICATIONS, 2021, 57 (54) : 6676 - 6679
[7] ALKYL SELENOVINYL ACETYLENE REACTION WITH CARBOXYLIC ACIDS
RADCHENKO, SI
ZHURNAL ORGANICHESKOI KHIMII, 1972, 8 (06): : 1329 - +
[8] Decarboxylative Functionalizations of Carboxylic Acids
Shibatomi, Kazutaka
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2025, 83 (02) : 14 - 24
[9] Ternary catalytic α-deuteration of carboxylic acids
Tanaka, T.
Koga, Y.
Honda, Y.
Tsuruta, A.
Matsunaga, N.
Koyanagi, S.
Ohdo, S.
Yazaki, R.
Ohshima, T.
NATURE SYNTHESIS, 2022, 1 (10): : 824 - 830
[10] Ternary catalytic α-deuteration of carboxylic acids
T. Tanaka
Y. Koga
Y. Honda
A. Tsuruta
N. Matsunaga
S. Koyanagi
S. Ohdo
R. Yazaki
T. Ohshima
Nature Synthesis, 2022, 1 : 824 - 830

← 1 2 3 4 5 →