Autistic traits and alcohol use in adolescents within the general population

被引：2

作者：

Pijnenburg, Lisa J. ^{[1
,2
]}

Kaplun, Anais ^{[3
]}

de Haan, Lieuwe ^{[2
]}

Janecka, Magdalena ^{[3
,4
]}

Smith, Lauren ^{[3
]}

Reichenberg, Abraham ^{[3
,4
]}

Banaschewski, Tobias ^{[5
]}

Bokde, Arun L. W. ^{[6
,7
]}

Quinlan, Erin Burke ^{[8
]}

Desrivieres, Sylvane ^{[8
]}

Grigis, Antoine ^{[9
]}

Garavan, Hugh ^{[10
,11
]}

Gowland, Penny ^{[12
]}

Heinz, Andreas ^{[13
,14
,15
,16
]}

Ittermann, Bernd ^{[17
,18
]}

Martinot, Jean-Luc ^{[19
,20
]}

Martinot, Marie-Laure Paillere ^{[19
,21
]}

Nees, Frauke ^{[5
,22
]}

Orfanos, Dimitri Papadopoulos ^{[9
]}

Paus, Tomas ^{[23
,24
]}

Poustka, Luise ^{[25
]}

Hohmann, Sarah ^{[5
]}

Millenet, Sabina ^{[5
]}

Froehner, Juliane H. ^{[26
,27
]}

Smolka, Michael N. ^{[26
,27
]}

Walter, Henrik ^{[13
,14
,15
,16
]}

Whelan, Robert ^{[28
,29
]}

Schumann, Gunter ^{[8
,30
,31
]}

Velthorst, Eva ^{[3
,4
]}

机构：

[1] GGZ Rivierduinen, Inst Mental Hlth Care, Leiden, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Psychiat, Meibergdreef 5, NL-1105 AZ Amsterdam, Netherlands

[3] Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA

[4] Seaver Autism Ctr Res & Treatment, New York, NY USA

[5] Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Child & Adolescent Psychiat & Psychotherapy, Sq J5, D-68159 Mannheim, Germany

[6] Trinity Coll Dublin, Sch Med, Discipline Psychiat, Dublin, Ireland

[7] Trinity Coll Dublin, Trinity Coll, Inst Neurosci, Dublin, Ireland

[8] Kings Coll London, Genet & Dev Psychiat Ctr, Inst Psychiat Psychol & Neurosci, Med Res Council Social, London, England

[9] Univ Paris Saclay, CEA, NeuroSpin, F-91191 Gif Sur Yvette, France

[10] Univ Vermont, Dept Psychiat, Burlington, VT 05405 USA

[11] Univ Vermont, Dept Psychol, Burlington, VT 05405 USA

[12] Univ Nottingham, Sir Peter Mansfield Imaging Ctr, Sch Phys & Astron, Univ Pk, Nottingham NG, England

[13] Charite Univ Med Berlin, Dept Psychiat & Psychotherapy, Charitepl 1, Berlin, Germany

[14] Free Univ Berlin, Charitepl 1, Berlin, Germany

[15] Humboldt Univ, Charitepl 1, Berlin, Germany

[16] Campus Charite Mitte, Berlin Inst Hlth, Charitepl 1, Berlin, Germany

[17] Phys Tech Bundesanstalt PTB, Braunschweig, Germany

[18] Phys Tech Bundesanstalt PTB, Berlin, Germany

[19] Maison de Solenn, Paris, France

[20] Sorbonne Univ, Univ Paris Descartes, INSERM Unit Neuroimaging & Psychiat 1000, Univ Paris Sud,Inst Natl Sante & Rech Med, Paris, France

[21] Hop La Pitie Salpetriere, AP HP, Dept Child & Adolescent Psychiat, Paris, France

[22] Heidelberg Univ, Med Fac Mannheim, Inst Cognit & Clin Neurosci, Cent Inst Mental Hlth, Sq J5, Mannheim, Germany

[23] Univ Toronto, Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Dept Psychol, Toronto, ON M6A 2E1, Canada

[24] Univ Toronto, Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Dept Psychiat, Toronto, ON M6A 2E1, Canada

[25] Univ Med Ctr Gottingen, Dept Child & Adolescent Psychiat & Psychotherapy, Von Siebold Str 5, D-37075 Gottingen, Germany

[26] Tech Univ Dresden, Dept Psychiat, Dresden, Germany

[27] Tech Univ Dresden, Neuroimaging Ctr, Dresden, Germany

[28] Trinity Coll Dublin, Sch Psychol, Dublin, Ireland

[29] Trinity Coll Dublin, Global Brain Hlth Inst, Dublin, Ireland

[30] Humboldt Univ, Dept Psychiat & Psychotherapy, PONS Res Grp, Campus Charite Mitte, Berlin, Germany

[31] Fudan Univ, Inst Sci & Technol Brain Inspired Intelligence IS, Shanghai, Peoples R China

来源：

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY | 2023年 / 32卷 / 09期

关键词：

Adolescence; Alcohol use; Autistic traits; Social preference; SUBSTANCE USE; SPECTRUM DISORDER; SOCIAL ANXIETY; CHILDREN; DIFFICULTIES; SYMPTOMS; ASSOCIATIONS; STRENGTHS; DEFICIT; HEALTH;

D O I：

10.1007/s00787-022-01970-3

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

It has been suggested that autistic traits are associated with less frequent alcohol use in adolescence. Our study seeks to examine the relationship between autistic traits and alcohol use in a large adolescent population. Leveraging data from the IMAGEN cohort, including 2045 14-year-old adolescents that were followed-up to age 18, we selected items on social preference/skills and rigidity from different questionnaires. We used linear regression models to (1) test the effect of the sum scores on the prevalence of alcohol use (AUDIT-C) over time, (2) explore the relationship between autistic traits and alcohol use patterns, and (3) explore the specific effect of each autistic trait on alcohol use. Higher scores on the selected items were associated with trajectories of less alcohol use from the ages between 14 and 18 (b = - 0.030; CI 95% = - 0.042, - 0.017; p < 0.001). Among adolescents who used alcohol, those who reported more autistic traits were also drinking less per occasion than their peers and were less likely to engage in binge drinking. We found significant associations between alcohol use and social preference (p < 0.001), nervousness for new situations (p = 0.001), and detail orientation (p < 0.001). Autistic traits (social impairment, detail orientation, and anxiety) may buffer against alcohol use in adolescence.

引用

页码：1633 / 1642

页数：10

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