IL-4 and IL-13 drive distinct and overlapping disease-associated signatures in cell types relevant to atopic dermatitis

被引：0
|
作者：
Srivatsan, S. [1 ]
Buonagurio, B. [1 ]
Nagashima, K. [1 ]
Asrat, S. [1 ]
Lim, W. K. [1 ]
Le Floc'h, A. [1 ]
Garcia, M. [1 ]
Zamolodchikov, D. [1 ]
Ajithdoss, D. [1 ]
Alessandri-Haber, N. [1 ]
Murphy, A. [1 ]
Sleeman, M. [1 ]
Orengo, J. [1 ]
机构：
[1] Regeneron Pharmaceut Inc, Tarrytown, NY USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2023年 / 143卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
208
引用
收藏
页码：S367 / S367
页数：1
相关论文
共 50 条
  • [41] Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls
    Miranda, Elena
    Roberts, Jennifer
    Novick, Steven
    Lapointe, Jean-Martin
    Bruijnzeel-Koomen, Carla
    Thijs, JudithL
    Sleeman, Matthew A.
    May, Richard D.
    Hijnen, DirkJan
    Strickland, Ian
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (02) : 440 - 443
  • [42] Identification of IL-4 regulated keratinocyte genes relevant in the pathogenesis of atopic dermatitis
    Bao, L.
    Chan, L. S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 : S3 - S3
  • [43] Distinct Structural Requirements for Interleukin-4 (IL-4) and IL-13 Binding to the Shared IL-13 Receptor Facilitate Cellular Tuning of Cytokine Responsiveness
    Ito, Takachika
    Suzuki, Shoichi
    Kanaji, Sachiko
    Shiraishi, Hiroshi
    Ohta, Shoichiro
    Arima, Kazuhiko
    Tanaka, Go
    Tamada, Taro
    Honjo, Eijiro
    Garcia, K. Christopher
    Kuroki, Ryota
    Izuhara, Kenji
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (36) : 24289 - 24296
  • [44] Bullous pemphigoid is associated with IL-4 and IL-5 and IL-13 deposition in vivo.
    Rico, MJ
    Benning, C
    Streilein, RD
    Hall, RP
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1996, 106 (04) : 280 - 280
  • [45] IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections
    Reece G Marillier
    Chesney Michels
    Elizabeth M Smith
    Lizette CE Fick
    Mosiuoa Leeto
    Benjamin Dewals
    William GC Horsnell
    Frank Brombacher
    BMC Immunology, 9
  • [46] IL-4 / IL-13 mediated cell-to-cell fusion in prostate cancer progress
    Uygur, Berna
    Leikina, Evgenia
    Chernomordik, Leonid
    CANCER RESEARCH, 2016, 76
  • [47] Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis
    Furue, Masutaka
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (15) : 1 - 25
  • [48] Flow cytometric analysis of IL-4, IL-13 and IFN-γ expression in peripheral blood mononuclear cells and detection of circulating IL-13 in patients with atopic dermatitis provide evidence for the involvement of type 2 cytokines in the disease
    Kaminishi, K
    Soma, Y
    Kawa, Y
    Mizoguchi, M
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2002, 29 (01) : 19 - 25
  • [49] Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression
    Yun, Hyeong Rok
    Ahn, Sang Woo
    Seol, Bomin
    Vasileva, Elena A.
    Mishchenko, Natalia P.
    Fedoreyev, Sergey A.
    Stonik, Valentin A.
    Han, Jin
    Ko, Kyung Soo
    Rhee, Byoung Doo
    Seol, Jung Eun
    Kim, Hyoung Kyu
    MARINE DRUGS, 2021, 19 (11)
  • [50] IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections
    Marillier, Reece G.
    Michels, Chesney
    Smith, Elizabeth M.
    Fick, Lizette C. E.
    Leeto, Mosiuoa
    Dewals, Benjamin
    Horsnell, William G. C.
    Brombacher, Frank
    BMC IMMUNOLOGY, 2008, 9 (1)
12345