Meta-analysis of risk factors associated with pharyngocutaneous fistulas following total laryngectomy

被引：0
|
作者：
Huang, Zhenhe [1 ]
Zhong, Huaping [2 ]
Cai, Yunxiang [1 ,3 ]
机构：
[1] Ganzhou Peoples Hosp, Dept Otolaryngol Head & Neck Surg, Ganzhou, Jiangxi, Peoples R China
[2] Gannan Med Coll, Affiliated Hosp 1, Dept Cardiovasc Med, Ganzhou, Jiangxi, Peoples R China
[3] Ganzhou Peoples Hosp, Dept Otolaryngol Head & Neck Surg, 16 Meiguan Ave, Ganzhou 341000, Jiangxi, Peoples R China
来源：
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH | 2023年 / 15卷 / 04期
关键词：
Pharyngocutaneous fistulas; total laryngectomy; risk factors; meta-analysis; SALVAGE TOTAL LARYNGECTOMY; MULTIVARIATE-ANALYSIS; PREDICTIVE FACTORS; RADIOTHERAPY; IMPACT; COMPLICATIONS; SURGERY; CANCER;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: To investigate the risk factors for pharyngocutaneous fistulas following total laryngectomy. Methods: PubMed, Web of Science, CNKI, Medline and Wanfang database were utilized to conduct a systematic literature research. Further, sensitivity and publication bias were analyzed to comprehensively estimate the risk factors associated with pharyngocutaneous fistulas following total laryngectomy. Results: Of the 112 studies identified, 25 were included in this analysis. The results showed that age (OR = 0.21, 95% CI 0.11-0.39, P<0.00001), smoking (OR = 3, 95% CI 1.54-5.84, P<0.00001), T-stage (OR = 0.3, 95% CI 0.22-0.4, P<0.00001), previous radiotherapy (OR = 0.31, 95% CI 0.23-0.44, P<0.000001) and preoperative albumin (OR = 0.28, 95% CI 0.16-0.47, P<0.00001) were risk factors associated with pharyngocutaneous fistulas. Conclusions: This review is a comprehensive analysis of the risk factors associated with pharyngocutaneous fistulas following total laryngectomy. Age, smoking, T-stage, previous radiotherapy and preoperative albumin were found to be the risk factors.
引用
收藏
页码：2281 / 2290
页数：10
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