Efficient method for the synthesis of novel methyl 4-cinnolinecarboxylate

被引:0
|
作者
Akbari, Ali [1 ]
Faryabi, Muhammad Saleh [1 ]
Tomar, Ravi [2 ]
机构
[1] Univ Jiroft, Fac Sci, Dept Chem, POB 8767161167, Jiroft, Iran
[2] SGT Univ, Fac Sci, Dept Chem, Gurugram 122505, Haryana, India
关键词
Heterocyclic compounds; Methyl; 4-cinnolinecarboxylate; Multicomponent reaction; Richter cyclization; Synthesis; CINNOLINE DERIVATIVES; CYCLIZATION; ANNULATION;
D O I
10.1007/s11030-022-10497-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new method is designed for the synthesis of some novel methyl 3-aryl/alkyl-4-cinnolinecarboxylate with developed a general Richter cyclization through diazotization strategy of commercially available 2-aryl/alkyl ethynyl aniline and methyl acetate. Most substrates were achieved in moderate to excellent yields in one-pot procedures under mild reaction conditions.
引用
收藏
页码:1401 / 1408
页数:8
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