COVID-19 outcomes in haemopoietic stem cell transplant recipients in Western Australia: the value of vaccination and antiviral therapy

被引:0
|
作者
Malherbe, Jacques A. J. [1 ,3 ]
Boan, Peter [2 ,4 ]
Purtill, Duncan [1 ,4 ]
Wright, Matthew [1 ,4 ]
Cannell, Paul [1 ,4 ]
Gangatharan, Shane A. [1 ,3 ,4 ]
Sidiqi, Hasib [1 ,4 ]
Cooney, Julian [1 ,4 ,5 ]
机构
[1] Fiona Stanley Hosp, Dept Haematol, Perth, WA, Australia
[2] Fiona Stanley Hosp, Dept Infect Dis, Perth, WA, Australia
[3] Univ Western Australia, Sch Biomed Sci, Perth, WA, Australia
[4] PathWest Lab Med Western Australia, Perth, WA, Australia
[5] Fiona Stanley Hosp, Dept Haematol, 11 Robin Warren Dr, Perth, WA 6150, Australia
关键词
COVID-19; bone marrow transplant; antiviral; vaccination;
D O I
10.1111/imj.16368
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Coronavirus-19 (COVID-19) mortality rates among haemopoietic stem cell transplant (HSCT) patients are high, ranging between 20% and 40%. We prospectively evaluated the mortality outcomes of COVID-19 in Western Australian HSCT patients. A total of 32/492 (6.5%) HSCT recipients contracted COVID-19 during the study, of whom 30/32 (94%) developed mild or asymptomatic disease. Two allogeneic HSCT patients were hospitalised for severe COVID-19; one patient died. Stringent healthcare, social isolation practices, aggressive vaccination programmes and rapid access to COVID-19 antivirals may have promoted mild COVID-19 illness in Western Australian HSCT patients, resulting in one of the lowest COVID-19 mortality rates in HSCT recipients worldwide.
引用
收藏
页码:664 / 670
页数:7
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