Five decades of Fontan palliation: What have we learned? What should we expect?

被引：3

作者：

Hassan, Adil ^{[1
]}

Chegondi, Madhuradhar ^{[2
]}

Porayette, Prashob ^{[3
]}

机构：

[1] Univ Iowa, Dept Internal Med, Iowa City, IA 52242 USA

[2] Univ Iowa, Stead Family Childrens Hosp, Div Pediat Crit Care Med, Iowa City, IA 52242 USA

[3] Univ Iowa, Stead Family Childrens Hosp, Div Pediat Cardiol, Iowa City, IA 52242 USA

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2023年 / 51卷 / 10期

关键词：

Single-ventricle physiology; Fontan; congenital heart disease; neurodevelopmental outcomes; adult congenital heart disease; arrhythmias; cyanosis; heart failure; cardiac transplantation; Fontan-associated liver disease; CONGENITAL HEART-DISEASE; PROTEIN-LOSING ENTEROPATHY; SINGLE VENTRICLE; CONSENSUS DOCUMENT; CLINICAL-OUTCOMES; AMERICAN-SOCIETY; VENOUS-PRESSURE; ARTERIAL DUCT; LONG-TERM; ADULTS;

D O I：

10.1177/03000605231209156

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The Fontan procedure is the final palliative surgery in a series of staged surgeries to reroute the systemic venous blood flow directly to the lungs, with the ventricle(s) pumping oxygenated blood to the body. Advances in medical and surgical techniques have improved patients' overall survival after the Fontan procedure. However, Fontan-associated chronic comorbidities are common. In addition to chronic cardiac dysfunction and arrhythmias, complications involving other organs such as the liver, lungs, intestine, lymphatic system, brain, and blood frequently occur. This narrative review focuses on the immediate and late consequences in children, pregnant women, and other adults with Fontan circulation. In addition, we describe the technical advancements that might change the way single-ventricle patients are managed in future.

引用

页数：17

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