BackgroundThe POSSUM model has been widely used to predict morbidity and mortality after general surgery. Modified versions known as O-POSSUM and P-POSSUM have been used extensively in orthopedic surgery, but their accuracy is unclear. This systematic review evaluated the predictive value of these models in older patients with hip fractures.MethodsThis study was performed and reported based on the "Preferred reporting items for systematic reviews and meta-analyses" guidelines. PubMed, Cochrane, EMBASE, and Web of Science were comprehensively searched for relevant studies, whose methodological quality was evaluated according to the "Methodological index for non-randomized studies" scale. Revman 5 was used to calculate weighted ratios of observed to expected morbidity or mortality.ResultsThe meta-analysis included 10 studies, of which nine (2549 patients) assessed the ability of O-POSSUM to predict postoperative morbidity, nine (3649 patients) assessed the ability of O-POSSUM to predict postoperative mortality, and four (1794 patients) assessed the ability of P-POSSUM to predict postoperative mortality. The corresponding weighted ratios of observed to expected morbidity or mortality were 0.84 (95% CI 0.70-1.00), 0.68 (95% CI 0.49-0.95), and 0.61 (95% CI 0.16-2.38).ConclusionsWhile O-POSSUM shows reasonable accuracy in predicting postoperative morbidity in older patients with hip fractures, both P-POSSUM and O-POSSUM substantially overestimate postoperative mortality. The POSSUM model should be optimized further for this patient population.
机构:Grp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Loc, P. Tran Ba
du Montcel, S. Tezenas
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Grp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Univ Paris 06, Er 4, Paris, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
du Montcel, S. Tezenas
Duron, J. J.
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Grp Hosp Pitie Salpetriere, Digest Surg & Transplantat Unit, AP HP, F-75651 Paris 13, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Duron, J. J.
Levard, H.
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Inst Monsouris, Gen & Digest Surg Unit, Paris, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Levard, H.
Suc, B.
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Ctr Hosp Univ Rangueil, Digest Surg Unit, Rangueil, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Suc, B.
Descottes, B.
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Ctr Hosp Univ Limoges, Visceral Surg & Transplantat Unit, Limoges, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Descottes, B.
Desrousseaux, B.
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Ctr Hosp Gen Lomme, Gen & Digest Surg Unit, Lomme Les Lille, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
Desrousseaux, B.
Hay, J. M.
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Hop Louis Mourier, Gen & Digest Surg Unit, AP HP, Paris, FranceGrp Hosp Pitie Salpetriere, Dept Sante Publ, Unite Biostat & Informat Med, AP HP, F-75651 Paris 13, France
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Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, SwedenOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Cao, Yang
Bass, Gary A.
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Orebro Univ, Fac Med & Hlth, Sch Med Sci, Dept Surg, Orebro, Sweden
Tallaght Univ Hosp, Dept Surg, Dublin, IrelandOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Bass, Gary A.
Ahl, Rebecka
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Orebro Univ, Fac Med & Hlth, Sch Med Sci, Dept Surg, Orebro, Sweden
Karolinska Univ Hosp, Dept Gen Surg, Stockholm, SwedenOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Ahl, Rebecka
Pourlotfi, Arvid
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Orebro Univ, Fac Med & Hlth, Sch Med Sci, Dept Surg, Orebro, Sweden
Orebro Univ Hosp, Dept Gen Surg, Orebro, SwedenOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Pourlotfi, Arvid
Geijer, Hakan
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Orebro Univ, Fac Med & Hlth, Dept Radiol, Orebro, SwedenOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Geijer, Hakan
Montgomery, Scott
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Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Karolinska Inst, Dept Med, Clin Epidemiol Div, S-17177 Stockholm, Sweden
UCL, Dept Epidemiol & Publ Hlth, London WC1E 6BT, EnglandOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden
Montgomery, Scott
Mohseni, Shahin
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Orebro Univ, Fac Med & Hlth, Sch Med Sci, Dept Surg, Orebro, Sweden
Orebro Univ Hosp, Dept Gen Surg, Orebro, SwedenOrebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70182 Orebro, Sweden