A Novel Composite Endpoint of Toxicity- and Progression-Free Survival after B-Cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Multiple Myeloma

被引：0
|
作者：
Mohty, Razan [1 ]
Junmin, Whiting [2 ]
Saha, Aditi [3 ]
Kim, Jongphil [2 ]
Nishihori, Taiga [1 ]
De Avila, Gabriel [4 ]
Corallo, Salvatore [1 ]
Dam, Marian [1 ]
Marin, Jessica [1 ]
Liu, Hien [5 ]
Mokhtari, Sepideh [6 ]
Jain, Michael D. [1 ]
Perna, Fabiana [7 ]
Blue, Brandon [3 ]
Grajales-Cruz, Ariel F. [4 ]
Castaneda, Omar [8 ]
Shain, Kenneth [4 ]
Baz, Rachid [3 ]
Freeman, Ciara Louise L. [8 ]
Alsina, Melissa [5 ]
Locke, Frederick L. [1 ,5 ]
Hansen, Doris K.
Lazaryan, Aleksandr [1 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Blood & Marrow Transplantat & Cellular Immun, Tampa, FL USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Biostat & Bioinformat, Tampa, FL USA
[3] H Lee Moffitt Canc Ctr & Res Inst, Dept Malignant Hematol, Tampa, FL USA
[4] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[5] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[6] H Lee Moffitt Canc Ctr & Res Inst, Dept Neurooncol, Tampa, FL USA
[7] H Lee Moffitt Canc Ctr & Res Inst, Dept Blood & Marrow Transplantat & Cellular Immun, Indianapolis, IN USA
[8] H Lee Moffitt Canc Ctr & Res Inst, Dept Blood & Marrow Transplant & Cellular Immunot, Tampa, FL USA
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-184406
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：5
相关论文
共 50 条
  • [41] B-Cell Maturation Antigen (BCMA) as a Biomarker for Assessing Multiple Myeloma Progression and Relapse
    Joshi, Hemant
    Wolters, Emily
    Firpo-Betancourt, Adolfo
    Mendu, Damodara Rao
    LABORATORY INVESTIGATION, 2024, 104 (03) : S1424 - S1425
  • [42] Updated results from CARTITUDE-1: Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T (CAR-T) cell therapy, in relapsed/refractory multiple myeloma (RRMM)
    Jagannath, Sundar
    Berdeja, Jesus G.
    Jakubowiak, Andrzej
    Agha, Mounzer
    Cohen, Adam
    Madduri, Deepu
    Hari, Parameswaran
    Yeh, Tzu-Min
    Olyslager, Yunsi
    Banerjee, Arnob
    Jackson, Carolyn C.
    Allred, Alicia
    Zudaire, Enrique
    Deraedt, William
    Wu, Xiaoling
    Pacaud, Lida
    Akram, Muhammad
    Lin, Yi
    Martin, Thomas
    Usmani, Saad Z.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S15 - S16
  • [43] A 5-Year Follow-up Clinical Study of the B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Therapy HDS269B in Patients with Relapsed or Refractory Multiple Myeloma
    Chen, Dongjian
    Zhu, Yu
    Chen, Zhi
    Jiang, Songfu
    He, Haiyan
    Qiang, Wanting
    Xiang, Fang
    Sun, Xuedong
    Du, Juan
    CLINICAL CANCER RESEARCH, 2024, 30 (17) : 3747 - 3756
  • [44] Early Time-to-Tocilizumab after B Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy in Myeloma
    Banerjee, Rahul
    Marsal, Jeffrey
    Huang, Chiung-Yu
    Lo, Mimi
    Kambhampati, Swetha
    Kennedy, Vanessa E.
    Arora, Shagun
    Wolf, Jeffrey L.
    Martin, Thomas G.
    Wong, Sandy W.
    Shah, Nina
    TRANSPLANTATION AND CELLULAR THERAPY, 2021, 27 (06): : 477.e1 - 477.e7
  • [45] B cell maturation antigen-specific chimeric antigen receptor T cells for relapsed or refractory multiple myeloma: A meta-analysis
    Gagelmann, Nico
    Ayuk, Francis
    Atanackovic, Djordje
    Kroeger, Nicolaus
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2020, 104 (04) : 318 - 327
  • [46] Chimeric antigen receptor (CAR) T-cell therapy for people with relapsed or refractory diffuse large B-cell lymphoma
    Ernst, Moritz
    Oeser, Annika
    Besiroglu, Burcu
    Caro-Valenzuela, Julia
    Aziz, Mohamed Abd El
    Monsef, Ina
    Borchmann, Peter
    Estcourt, Lise J.
    Skoetz, Nicole
    Goldkuhle, Marius
    COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2021, (09):
  • [47] Chimeric antigen receptor T-cell treatment patterns in relapsed or refractory large B-cell lymphoma
    Seyedin, Roxanna
    Snider, Julia T.
    Rajagopalan, Krithika
    Wade, Sally W.
    Gergis, Usama
    FUTURE ONCOLOGY, 2023, 19 (22) : 1535 - 1547
  • [48] Factors Associated with Costs in Chimeric Antigen Receptor T-Cell Therapy for Patients with Relapsed/Refractory B-Cell Malignancies
    Zhu, Feng
    Wei, Guoqing
    Zhang, Mingming
    Zhao, Houli
    Wu, Wenjun
    Yang, Luxin
    Hu, Yongxian
    Huang, He
    CELL TRANSPLANTATION, 2020, 29
  • [49] B-cell maturation antigen chimeric antigen receptor-T therapy alleviated heart failure in patients with multiple myeloma
    Wang, Yunhong
    Zhang, Ke
    Suo, Xiaohui
    Meng, Ning
    Gu, Yuanrui
    Qin, Yilang
    Tu, Yanxia
    Zhang, Xiaohui
    Sun, Guofeng
    Ji, Jiaojiao
    Wu, Weichun
    Cai, Yuqi
    Yang, Kai
    Ouyang, Chenxi
    Qi, Junyuan
    ESC HEART FAILURE, 2024, 11 (01): : 574 - 580
  • [50] Development of a B-cell maturation antigen-specific T-cell antigen coupler receptor for multiple myeloma
    Bezverbnaya, Ksenia
    Moogk, Duane
    Cummings, Derek
    Baker, Christopher L.
    Aarts, Craig
    Denisova, Galina
    Sun, Michael
    McNicol, Jamie D.
    Turner, Rebecca C.
    Rullo, Anthony F.
    Foley, S. Ronan
    Bramson, Jonathan L.
    CYTOTHERAPY, 2021, 23 (09) : 820 - 832
12345