TET2 CLONAL HEMATOPOIESIS MUTATIONS ARE ENRICHED AMONG RECIPIENTS OF SOLID-ORGAN TRANSPLANTS

被引：0
|
作者：
Silver, A. [1 ]
Vlasschaert, C. [2 ]
Sharber, B. [3 ]
Xu, Y. [4 ,5 ,6 ]
Bick, A. [1 ,3 ]
Savona, M. [1 ,7 ,8 ,9 ]
机构：
[1] Vanderbilt Univ, Sch Med, Program Canc Biol, Nashville, TN USA
[2] Queens Univ, Dept Med, Kingston, ON, Canada
[3] Vanderbilt Univ, Sch Med, Div Med Genet, Nashville, TN USA
[4] Vanderbilt Univ, Sch Med, Dept Biomed Informat, Nashville, TN USA
[5] Vanderbilt Univ, Sch Med, Dept Biostat, Nashville, TN USA
[6] Vanderbilt Univ, Sch Med, Ctr Quantitat Sci, Nashville, TN USA
[7] Vanderbilt Univ, Sch Med, Div Hematol Oncol, Nashville, TN USA
[8] Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[9] Vanderbilt Univ, Sch Med, Ctr Immunobiol, Nashville, TN USA
来源：
LEUKEMIA RESEARCH | 2023年 / 128卷
关键词：
D O I：
10.1016/j.leukres.2023.107162
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P027
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Blockade Of IL-6 Signaling Alleviates Atherosclerosis In Tet2 Deficient Clonal Hematopoiesis
    Liu, Wenli
    Wang, Nan
    Tall, Alan
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 43
  • [32] THE IDENTIFICATION OF VULNERABILITIES IN CLONAL HEMATOPOIESIS USING A HUMAN MODEL OF TET2 LOSS-OF-FUNCTION
    Boileau, Meaghan
    Shan, Yufan
    Marinaccio, Christian
    Apazidis, Athina
    Kim, Peter Geon
    Ebert, Benjamin
    Armstrong, Scott
    EXPERIMENTAL HEMATOLOGY, 2024, 137
  • [33] TET2 Driven Clonal Hematopoiesis Promotes Allograft Tolerance in a Mouse Heart Transplant Model
    Hahn, L. R. Gokanapudy
    Yang, S.
    Bredemeyer, A.
    Dun, H.
    Lokshina, I.
    Kadyrov, F.
    Adamo, L.
    Kreisel, D.
    Lavine, K. J.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2021, 40 (04): : S228 - S228
  • [34] THE IDENTIFICATION OF VULNERABILITIES IN CLONAL HEMATOPOIESIS USING A HUMAN MODEL OF TET2 LOSS-OF-FUNCTION
    Boileau, Meaghan
    Shan, Yufan
    Marinaccio, Christian
    Apazidis, Athina
    Kim, Peter Geon
    Ebert, Benjamin
    Armstrong, Scott
    EXPERIMENTAL HEMATOLOGY, 2024, 137
  • [35] TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis
    Tulstrup, Morten
    Soerensen, Mette
    Hansen, Jakob Werner
    Gillberg, Linn
    Needhamsen, Maria
    Kaastrup, Katja
    Helin, Kristian
    Christensen, Kaare
    Weischenfeldt, Joachim
    Gronbaek, Kirsten
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [36] TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis
    Morten Tulstrup
    Mette Soerensen
    Jakob Werner Hansen
    Linn Gillberg
    Maria Needhamsen
    Katja Kaastrup
    Kristian Helin
    Kaare Christensen
    Joachim Weischenfeldt
    Kirsten Grønbæk
    Nature Communications, 12
  • [37] Clonal Hematopoiesis Associated With TET2 and DNMT3A Gene Driver Mutations Accelerates Aortic Valve Calcification in vitro and in vivo
    Abplanalp, Wesley T.
    Schuhmacher, Bianca
    Mas-Peiro, Silvia
    Zuriaga, Maria A.
    Matesanz, Nuria
    Fuster, Jose J.
    John, David
    Muhly-Reinholz, Marion
    Vasa-Nicotera, Mariuca
    Merten, Maximilian
    Hoffmann, Jedrzej
    Zeiher, Andreas M.
    Dimmeler, Stefanie
    CIRCULATION, 2022, 146
  • [38] Fatal Chagas Disease Among Solid-Organ Transplant Recipients in Colombia
    Fernando Gomez-P, Carlos
    Cesar Mantilla-H, Julio
    Rodriguez-Morales, Alfonso J.
    OPEN FORUM INFECTIOUS DISEASES, 2014, 1 (01):
  • [39] Cancer Mortality Among Recipients of Solid-Organ Transplantation in Ontario, Canada
    Acuna, Sergio A.
    Fernandes, Kimberly A.
    Daly, Corinne
    Hicks, Lisa K.
    Sutradhar, Rinku
    Kim, S. Joseph
    Baxter, Nancy N.
    JAMA ONCOLOGY, 2016, 2 (04) : 463 - 469
  • [40] Sole DNMT3A/TET2/ASXL1 Mutations Define a Distinct Clinical Trajectory for Patients with Clonal Hematopoiesis
    Patel, Shyam Ajay
    Gerber, William K.
    Zheng, Rena
    Khanna, Shrinkhala
    Hutchinson, Lloyd
    Cerny, Jan
    Dasilva, Brandon
    Zhang, Tian Y.
    Khedr, Salwa
    Selove, William
    Woda, Bruce
    Abel, Gregory A.
    Miron, Patricia Minehart
    Higgins, Anne
    Gerber, Jonathan M.
    BLOOD, 2023, 142
12345