Efficacy and safety of sintilimab plus bevacizumab in metastatic nasopharyngeal carcinoma after failure of platinum-based chemotherapy: An open-label phase II study.

被引：0
|
作者：
Lu, Nian
Jiang, Yao-Fei
Xia, Weixiong
Huang, Ying
Xie, Chuan-Miao
Xu, Cheng
Ye, Yan-Fang
Liu, Guo-Ying
Bei, Wei-Xin
Ke, Liang-Ru
Li, Wang-Zhong
Wang, Xin
Xie, Changqing
Liang, Hu
Xiang Yanqun
机构：
[1] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, Canc Ctr, State Key Lab Oncol South China, Guangzhou, Peoples R China
[2] Sun Yat Sen Univ, State Key Lab Oncol South China, Collaborat Innovat Ctr Canc Med, Ctr Canc, Guangzhou, Peoples R China
[3] Sun Yat Sen Univ, Ctr Canc,Guangdong Key Lab Nasopharyngeal Carcino, State Key Lab Oncol South China, Collaborat Innovat Ctr Canc Med, Guangzhou, Peoples R China
[4] Sun Yat Sen Univ, Ctr Canc, Guangzhou, Peoples R China
[5] Sun Yat Sen Univ, Dept Radiat Oncol, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China,Canc Ctr, Guangzhou, Peoples R China
[6] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Clin Res Design Div, Guangzhou, Peoples R China
[7] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou, Peoples R China
[8] Sun Yat Sen Univ, Dept Nasopharyngeal Carcinoma, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China,Canc Ctr, Guangzhou, Peoples R China
[9] Sun Yat Sen Univ, Dept Med Imaging, Ctr Canc, Guangzhou, Peoples R China
[10] Guangzhou Med Univ, Affiliated Hosp 1, Dept Thorac Surg & Oncol,Guangzhou Inst Resp Hlth, Natl Clin Res Ctr Resp Dis,State Key Lab Resp Dis, Guangzhou, Peoples R China
[11] NCI, Thorac & GI Malignancies Branch, Ctr Canc Res, NIH, Bethesda, OH USA
[12] NCI, Thorac & GI Malignancies Branch, Ctr Canc Res, NIH, Bethesda, MD USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2023年 / 41卷 / 16期
基金：
中国国家自然科学基金;
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
6031
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Efficacy and safety of single-agent sunitinib in treating patients with advanced hepatocelluar carcinoma after sorafenib failure: A prospective, open-label, phase II study.
    Yau, T.
    Leung, R. C.
    Wong, H.
    Chiu, J.
    Chan, P.
    Pang, R.
    Fan, S. T.
    Poon, R. T. P.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [22] Efficacy of Platinum Rechallenge in Metastatic Urothelial Carcinoma After Previous Platinum-Based Chemotherapy for Metastatic Disease
    Wong, Risa L.
    Ferris, Lorin A.
    Do, Olivia A.
    Holt, Sarah K.
    Ramos, Jorge D.
    Crabb, Simon J.
    Sternberg, Cora N.
    Bellmunt, Joaquim
    Ladoire, Sylvain
    De Giorgi, Ugo
    Harshman, Lauren C.
    Vaishampayan, Ulka N.
    Necchi, Andrea
    Srinivas, Sandy
    Pal, Sumanta K.
    Niegisch, Guenter
    Dorff, Tanya B.
    Galsky, Matthew D.
    Yu, Evan Y.
    ONCOLOGIST, 2021, : 1026 - 1034
  • [23] Nimotuzumab combined with cisplatin plus fluorouracil chemotherapy in patients with metastatic nasopharyngeal carcinoma after radical radiotherapy: A multicentre, open-label, phase II clinical trial.
    Zhao, Chong
    Miao, Jingjing
    Shen, Guanzhu
    Li, Jin-Gao
    Zhang, Ning
    Shi, Mei
    Wang, Lin
    Hu, Guoqing
    Chen, Xiaozhong
    Hu, Xuefeng
    Wu, Shi Xiu
    Chen, Jiaxin
    Shao, Xunfan
    Xie, Conghua
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [24] Efficacy and safety of first-line sintilimab plus anlotinib versus chemotherapy for metastatic non-small cell lung cancer: a phase II, open-label, randomized controlled trial
    Chu, Tianqing
    Zhong, Hua
    Yu, Zhuang
    Wang, Jing
    Zhao, Yanqiu
    Mu, Xiaoqian
    Yu, Xinmin
    Shi, Xun
    Shi, Qingming
    Guan, Maojing
    Ding, Cuimin
    Geng, Nan
    Qian, Jialin
    Han, Baohui
    CANCER COMMUNICATIONS, 2025,
  • [25] An Open-Label, Randomized Phase II Trial of Personalized Peptide Vaccination in Patients with Bladder Cancer that Progressed after Platinum-Based Chemotherapy
    Noguchi, Masanori
    Matsumoto, Kazumasa
    Uemura, Hirotsugu
    Arai, Gaku
    Eto, Masatoshi
    Naito, Seiji
    Ohyama, Chikara
    Nasu, Yasutomo
    Tanaka, Masatoshi
    Moriya, Fukuko
    Suekane, Shigetaka
    Matsueda, Satoko
    Komatsu, Nobukazu
    Sasada, Tetsuro
    Yamada, Akira
    Kakuma, Tatsuyuki
    Itoh, Kyogo
    CLINICAL CANCER RESEARCH, 2016, 22 (01) : 54 - 60
  • [26] Bevacizumab plus platinum-based chemotherapy in advanced non-squamous non-small-cell lung cancer: a randomized, open-label phase 2 study (CLEAR)
    Udagawa, Hibiki
    Sugiyama, Eri
    Harada, Toshiyuki
    Atagi, Shinji
    Koyama, Ryo
    Watanabe, Satoshi
    Nakamura, Yukiko
    Harada, Daijiro
    Hataji, Osamu
    Tanaka, Fumihiro
    Kida, Hiroshi
    Satouchi, Miyako
    Maeno, Ken
    Inoue, Akira
    Yoh, Kiyotaka
    Yamane, Yuki
    Urata, Yoshiko
    Yoshioka, Hiroshige
    Yamanaka, Takeharu
    Goto, Koichi
    TRANSLATIONAL LUNG CANCER RESEARCH, 2021, 10 (07) : 3059 - +
  • [27] Bevacizumab and platinum-based combinations for recurrent ovarian cancer: a randomised, open-label, phase 3 trial
    Pfisterer, Jacobus
    Shannon, Catherine M.
    Baumann, Klaus
    Rau, Joern
    Harter, Philipp
    Joly, Florence
    Sehouli, Jalid
    Canzler, Ulrich
    Schmalfeldt, Barbara
    Dean, Andrew P.
    Hein, Alexander
    Zeimet, Alain G.
    Hanker, Lars C.
    Petit, Thierry
    Marme, Frederik
    El-Balat, Ahmed
    Glasspool, Rosalind
    de Gregorio, Nikolaus
    Mahner, Sven
    Meniawy, Tarek M.
    Park-Simon, Tjoung-Won
    Mouret-Reynier, Marie-Ange
    Costan, Cristina
    Meier, Werner
    Reinthaller, Alexander
    Goh, Jeffrey C.
    L'Haridon, Tifenn
    Hay, Sally Baron
    Kommoss, Stefan
    du Bois, Andreas
    Kurtz, Jean-Emmanuel
    LANCET ONCOLOGY, 2020, 21 (05): : 699 - 709
  • [28] First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients
    Smith, I. E.
    Pierga, J. -Y.
    Biganzoli, L.
    Cortes-Funes, H.
    Thomssen, C.
    Pivot, X.
    Fabi, A.
    Xu, B.
    Stroyakovskiy, D.
    Franke, F. A.
    Kaufman, B.
    Mainwaring, P.
    Pienkowski, T.
    De Valk, B.
    Kwong, A.
    Gonzalez-Trujillo, J. L.
    Koza, I.
    Petrakova, K.
    Pereira, D.
    Pritchard, K. I.
    ANNALS OF ONCOLOGY, 2011, 22 (03) : 595 - 602
  • [29] Efficacy and safety of sintilimab plus albumin-bound- paclitaxel in recurrent or metastatic cervical cancer: a multicenter, open-label, single-arm, phase II trial
    Wang, Yin
    Zhao, Jing
    Liang, Haixi
    Liu, Junxiu
    Huang, Shenjiao
    Zou, Guorong
    Huang, Xin
    Lan, Chunyan
    ECLINICALMEDICINE, 2023, 65
  • [30] OVARIO: A single-arm, open-label phase II study of maintenance therapy with niraparib plus bevacizumab (bev) in patients (pts) with advanced ovarian cancer (OC) after response to frontline platinum-based chemotherapy (chemo)
    Hardesty, M.
    Hope, J. M.
    Krivak, T.
    Chen, J.
    Wainszelbaum, M.
    Gupta, D.
    Richardson, D.
    ANNALS OF ONCOLOGY, 2018, 29
12345