Progress in the Detection of Cerebrospinal Fluid by Raman Spectroscopy

被引：2

作者：

Song, Yali ^{[1
]}

Bian, Handan ^{[1
]}

Zeng, Tingting ^{[1
,3
]}

Lin, Ting ^{[2
]}

Liu, Yuxin ^{[1
]}

Deng, Shanying ^{[1
]}

Liao, Juan ^{[1
]}

Mao, Zhigang ^{[1
]}

Chen, Si ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp, Dept Lab Med, Chengdu, Sichuan, Peoples R China

[2] Sichuan Univ, West China Hosp, Dept Hematol, Res Lab Hematol, Chengdu, Sichuan, Peoples R China

[3] Sichuan Univ, West China Hosp, Dept Lab Med, 37 Guoxue Xiang, Chengdu, Sichuan, Peoples R China

来源：

CURRENT NANOSCIENCE | 2023年 / 19卷 / 03期

关键词：

Raman spectroscopy; cerebrospinal fluid; nanostructure; Alzheimer's disease; dopamine; neurodegeneration; ALZHEIMERS-DISEASE; PARKINSONS-DISEASE; SELECTIVE SEPARATION; CLINICAL-FEATURES; DIAGNOSTIC-TOOL; SERS DETECTION; MENINGITIS; BIOMARKERS; DOPAMINE; PROTEIN;

D O I：

10.2174/1573413718666220803141856

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

As a precious sterile body fluid, cerebrospinal fluid (CSF) examination plays an important role in the diagnosis of many clinical diseases. Early diagnosis can significantly improve these diseases' survival rate. Raman spectroscopy is a scattering spectrum that has been used for the research and analysis of molecular structures. It has been widely used in many fields, such as protein detection, tumor genes, microbiological pathogen compound materials, and food and medical monitoring, with high sensitivity and specificity. In this review, we briefly introduce the mechanism of Raman spectroscopy and summarize its progress in detecting cerebrospinal fluid, mainly focusing on the application of neurodegenerative diseases by Raman spectroscopy. Meanwhile, we also prospect the development of Raman spectroscopy in the detection of CSF and other fluids.

引用

页码：338 / 349

页数：12

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