Machine learning and artificial intelligence in research and healthcare

Artificial intelligence (AI) is a broad term referring to the application of computational algorithms that can analyze large data sets to classify, predict, or gain useful conclusions. Under the umbrella of AI is machine learning (ML). ML is the process of building or learning statistical models using previously observed real world data to predict outcomes, or categorize observations based on 'training' provided by humans. These predictions are then applied to future data, all the while folding in the new data into its perpetually improving and calibrated statistical model. The future of AI and ML in healthcare research is exciting and expansive. AI and ML are becoming cornerstones in the medical and healthcare-research domains and are integral in our continued processing and capitalization of robust patient EMR data. Considerations for the use and application of ML in healthcare settings include assessing the quality of data inputs and decision-making that serve as the foundations of the ML model, ensuring the end-product is interpretable, transparent, and ethical concerns are considered throughout the development process. The current and future applications of ML include improving the quality and quantity of data collected from EMRs to improve registry data, utilizing these robust datasets to improve and standardized research protocols and outcomes, clinical decision-making applications, natural language processing and improving the fundamentals of value-based care, to name only a few. (c) 2022 Elsevier Ltd. All rights reserved.