Atroposelective Synthesis of N-N Axially Chiral Bipyrroles via Rhodium-Catalyzed C-H Insertion Reaction

被引：20
|
作者：
Wang, Changkai [1 ]
Sun, Jiangtao [1 ]
机构：
[1] Changzhou Univ, Sch Petrochem Engn, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 26期
关键词：
ENANTIOSELECTIVE SYNTHESES; ATROPISOMERS; CONSTRUCTION; ARYLATION; ACCESS;
D O I：
10.1021/acs.orglett.3c01509
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An atroposelective synthesis of bipyrroleswith an axially chiralN-N bond has been established via a rhodium-catalyzed C-Hbond insertion reaction to provide the desired atropisomers in goodyields (up to 97% yield) with good to excellent enantioselectivities(up to 99% ee).
引用
收藏
页码：4808 / 4812
页数：5
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