Pan-TRK Immunohistochemistry to Optimize the Detection of NTRK Fusions: Removing the Hay When Looking for the Needle

被引：2
|
作者：
Conde, Esther [1 ]
Hernandez, Susana [2 ]
Alonso, Marta [2 ]
Lopez-Rios, Fernando [1 ]
机构：
[1] Univ Complutense Madrid, Hosp Univ 12 Octubre, Res Inst Hosp 12 Octubre I 12, Pathol Dept,CIBERONC, Madrid, Spain
[2] Hosp Univ 12 Octubre, Res Inst Hosp 12 Octubre I 12, Pathol Dept, CIBERONC, Madrid, Spain
来源：
MODERN PATHOLOGY | 2023年 / 36卷 / 12期
关键词：
immunohistochemistry; NTRK; predictive biomarkers; NEXT-GENERATION; GENE FUSIONS; SOLID TUMORS; RECOMMENDATIONS; REARRANGEMENTS;
D O I：
10.1016/j.modpat.2023.100346
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
引用
收藏
页数：3
相关论文
共 40 条
  • [31] Pan-Trk immunohistochemistry reliably identifies ETV6-NTRK3 fusion in secretory carcinoma of the salivary gland
    Diana Bell
    Renata Ferrarotto
    Li Liang
    Ryan P. Goepfert
    Jie Li
    Jing Ning
    Russell Broaddus
    Randal S. Weber
    Adel K. El-Naggar
    Virchows Archiv, 2020, 476 : 295 - 305
  • [32] Screening for NTRK-rearranged Tumors Using Immunohistochemistry: Comparison of 2 Different pan-TRK Clones in Melanoma Samples
    Bourhis, Amelie
    Redoulez, Geoffroy
    Quintin-Roue, Isabelle
    Marcorelles, Pascale
    Uguen, Arnaud
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2020, 28 (03) : 194 - 196
  • [33] Using pan-TRK and RET Immunohistochemistry for the Detection of Fusion Types of Salivary Gland Secretory Carcinoma
    Su, Yu-Ju
    Lee, Yi-Hsuan
    Jin, Ying-Tai
    Hsieh, Min-Shu
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2022, 30 (04) : 264 - 272
  • [34] Fluorescent In Situ Hybridization Must be Preferred to pan-TRK Immunohistochemistry to Diagnose NTRK3-rearranged Gastrointestinal Stromal Tumors (GIST)
    Castillon, Marine
    Kammerer-Jacquet, Solene-Florence
    Cariou, Melanie
    Costa, Sebastian
    Conq, Gwenael
    Samaison, Laura
    Douet-Guilbert, Nathalie
    Marcorelles, Pascale
    Doucet, Laurent
    Uguen, Arnaud
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2021, 29 (08) : 626 - 634
  • [35] Pan-Trk immunohistochemistry is a sensitive and specific ancillary tool for diagnosing secretory carcinoma of the salivary gland and detecting ETV6-NTRK3 fusion
    Xu, Bin
    Al Rasheed, Mohamed R. Haroon
    Antonescu, Cristina R.
    Alex, Deepu
    Frosina, Denise
    Ghossein, Ronald
    Jungbluth, Achim A.
    Katabi, Nora
    HISTOPATHOLOGY, 2020, 76 (03) : 375 - 382
  • [36] Utility of Pan-TRK Immunohistochemistry (IHC) as an Ancillary Tool in Diagnosing Secretory Carcinoma (SC) of Salivary Gland and Detecting ETV6-NTRK3 fusion
    Al Rasheed, Mohamed Rizwan Haroon
    Xu, Bin
    Antonescu, Cristina
    Alex, Deepu
    Frosina, Denise
    Ghossein, Ronald
    Jungbluth, Achim
    Katabi, Nora
    LABORATORY INVESTIGATION, 2019, 99
  • [37] Utility of Pan-TRK Immunohistochemistry (IHC) as an Ancillary Tool in Diagnosing Secretory Carcinoma (SC) of Salivary Gland and Detecting ETV6-NTRK3 fusion
    Al Rasheed, Mohamed Rizwan Haroon
    Xu, Bin
    Antonescu, Cristina
    Alex, Deepu
    Frosina, Denise
    Ghossein, Ronald
    Jungbluth, Achim
    Katabi, Nora
    MODERN PATHOLOGY, 2019, 32
  • [38] ICP-723 is a potent pan-TRK Inhibitor with robust anti-tumor activities against wild-type and acquired drug-resistant mutations of NTRK fusions
    Liang, Ruixia
    Zhou, Chao
    Han, Yingrui
    Lu, Prince
    Wang, Charles Ying
    Wang, Zuopeng
    Liu, Richard
    Kong, Norman
    Zhang, Jason Bing
    Cui, Jasmine Jisong
    Ouyang, Davy Xuesong
    CANCER RESEARCH, 2022, 82 (12)
  • [39] Immunohistochemical Detection of pan-Tropomyosin Receptor Kinase (pan-TRK) Expression in Solid Tumor Specimens: Inter-Laboratory and Inter-Reader Agreement in NGS-confirmed NTRK Fusion-Positive and Fusion-Negative Cases
    Stratton, Steven
    Feng, Janine
    Liu, Wen-Wei
    Thorne-Nuzzo, Trish
    Kockx, Mark
    Penault-Llorca, Frederique
    Stenzinger, Albrecht
    Glade, Julia
    Lopez-Rios, Fernando
    Conde, Esther
    Viale, Giuseppe
    Soares, Fernando
    Chou, Teh-Ying
    MODERN PATHOLOGY, 2021, 34 (SUPPL 2) : 518 - 519
  • [40] Immunohistochemical Detection of pan-Tropomyosin Receptor Kinase (pan-TRK) Expression in Solid Tumor Specimens: Inter-Laboratory and Inter-Reader Agreement in NGS-confirmed NTRK Fusion-Positive and Fusion-Negative Cases
    Stratton, Steven
    Feng, Janine
    Liu, Wen-Wei
    Thorne-Nuzzo, Trish
    Kockx, Mark
    Penault-Llorca, Frederique
    Stenzinger, Albrecht
    Glade, Julia
    Lopez-Rios, Fernando
    Conde, Esther
    Viale, Giuseppe
    Soares, Fernando
    Chou, Teh-Ying
    LABORATORY INVESTIGATION, 2021, 101 (SUPPL 1) : 518 - 519
1234