Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled

被引:1
|
作者
Franchino, Camilla Aurora [1 ,2 ,3 ]
Motori, Elisa [1 ,2 ,3 ,4 ]
Bergami, Matteo [2 ,3 ,4 ]
机构
[1] Univ Cologne, Inst Biochem, D-50674 Cologne, Germany
[2] Univ Cologne, Cologne Excellence Cluster Cellular Stress Respons, Fac Med,, Cologne, Germany
[3] Univ Cologne, Univ Hosp Cologne, D-50931 Cologne, Germany
[4] Ctr Mol Med, D-50931 Cologne, Germany
关键词
D O I
10.1038/s41392-023-01730-y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页数:2
相关论文
共 47 条
  • [31] Mitofusin-2, mutated in Charcot-Marie-Tooth type IIa, links endoplasmic reticulum to mitochondria
    de Brito, O. Martins
    Scorrano, L.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2006, : 523 - 523
  • [32] Increased Ca2+ transport across the mitochondria-associated membranes by Mfn2 inhibiting endoplasmic reticulum stress in ischemia/reperfusion kidney injury (vol 13, 17257, 2023)
    Wang, Shun
    Sang, Xiaohong
    Li, Suhua
    Yang, Wenjun
    Wang, Shihan
    Chen, Haixia
    Lu, Chen
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [33] Mitofusin 2-tethering mitochondria and endoplasmic reticulum controls G0/G1-phase cell cycle arrest in vascular smooth muscle cells
    Li, Dan
    Guo, Xiaomei
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, 34 : S42 - S42
  • [34] Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells
    Wang, Weilin
    Xie, Qingsong
    Zhou, Xiaohu
    Yao, Jingzi
    Zhu, Xiaoxiang
    Huang, Pengfei
    Zhang, Lufei
    Wei, Jianfeng
    Xie, Haiyang
    Zhou, Lin
    Zheng, Shusen
    CANCER LETTERS, 2015, 358 (01) : 47 - 58
  • [35] Mitofusin-2-mediated tethering of mitochondria and endoplasmic reticulum promotes cell cycle arrest of vascular smooth muscle cells in G0/G1 phase
    Li, Dan
    Li, Xiaolan
    Guan, Yang
    Gao, Xiaomei
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2015, 47 (06) : 441 - 450
  • [36] Excitation of Mitochondria-Endoplasmic Reticulum Ca2+ Coupling by Femtosecond-Laser Photostimulation (vol 12, 3700308, 2018)
    Shi, Fan
    Wang, Shaoyang
    Zhu, Yujie
    He, Hao
    IEEE PHOTONICS JOURNAL, 2020, 12 (05):
  • [37] Phthalates Induce Neurotoxicity by Disrupting the Mfn2-PERK Axis-Mediated Endoplasmic Reticulum-Mitochondria Interaction
    Zhao, Yi
    Chang, Yuan-Hang
    Ren, Hao-Ran
    Lou, Ming
    Jiang, Fu-Wei
    Wang, Jia-Xin
    Chen, Ming-Shan
    Liu, Shuo
    Shi, Yu-Sheng
    Zhu, Hong-Mei
    Li, Jin-Long
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 72 (13) : 7411 - 7422
  • [38] Mitigation of lipopolysaccharide-induced intestinal injury in rats by Chimonanthus nitens Oliv. essential oil via suppression of mitochondrial fusion protein mitofusin 2 (MFN2)-mediated mitochondrial-associated endoplasmic reticulum membranes (MAMs) formation
    Huang, Shuying
    Zeng, Zhenguo
    Chu, Yuelei
    Zhang, Shichao
    Zhou, Jia
    Hu, Zhiguo
    Yang, Yuting
    Zhou, Chaoqi
    Cheng, Wang
    Yang, Songyu
    Chen, Shengbin
    Li, Wenjuan
    Qing, Cheng
    JOURNAL OF ETHNOPHARMACOLOGY, 2025, 337
  • [39] c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration
    Martinez, Alexis
    Lamaizon, Cristian M.
    Valls, Cristian
    Llambi, Fabien
    Leal, Nancy
    Fitzgerald, Patrick
    Guy, Cliff
    Kaminski, Marcin M.
    Inestrosa, Nibaldo C.
    van Zundert, Brigitte
    Cancino, Gonzalo I.
    Dulcey, Andres E.
    Zanlungo, Silvana
    Marugan, Juan J.
    Hetz, Claudio
    Green, Douglas R.
    Alvarez, Alejandra R.
    ANTIOXIDANTS, 2023, 12 (11)
  • [40] Regulation of Endoplasmic Reticulum-Mitochondria Tethering and Ca2+ Fluxes by TDP-43 via GSK3β
    Peggion, Caterina
    Massimino, Maria Lina
    Bonadio, Raphael Severino
    Lia, Federica
    Lopreiato, Raffaele
    Cagnin, Stefano
    Cali, Tito
    Bertoli, Alessandro
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)