Access to Fully Substituted Dihydroindazoles Via Hexadehydro-Diels-Alder/[3+2] Cycloaddition

被引：2

作者：

Xu, Weigang ^{[1
]}

Li, Xiuhuan ^{[2
]}

Zou, Luyao ^{[1
]}

Li, Xiaoli ^{[1
]}

Zhang, Zhiqiang ^{[1
]}

Ali, Sajjad ^{[1
]}

Wang, Zhengshen ^{[1
]}

Li, Pengfei ^{[1
]}

Zheng, Huaiji ^{[1
]}

机构：

[1] Northwest Agr & Forestry Univ, Shaanxi Key Lab Nat Prod & Chem Biol, Coll Chem & Pharm, Yangling 712100, Peoples R China

[2] Northwest Agr & Forestry Univ, State Key Lab Crop Stress Biol Arid Areas, Yangling 712100, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 20期

基金：

中国国家自然科学基金;

关键词：

1,3-DIPOLAR CYCLOADDITION; 1H-INDAZOLES; ARYNES; INDAZOLES; CYCLOAROMATIZATION; EFFICIENT; BENZYNES;

D O I：

10.1021/acs.joc.3c01901

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cascade hexadehydro-Diels-Alder (HDDA)/[3 + 2] cycloaddition reaction between tetrayne and N,N '-cyclic acylhydrazone is described. This strategy allows the efficient construction of fully substituted 2,3-dihydro-1H-indazole scaffolds which have insecticidal activity against the third instar larvae of Mythimna separata.

引用

页码：14736 / 14747

页数：12

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