Older and wiser: The benefits to neonates of aged neutrophils

被引：0
|
作者：
Collins, George B. [1 ,2 ]
Gilroy, Derek [1 ]
机构：
[1] UCL, Dept Expt Med & Therapeut, Div Med, London, England
[2] St Bartholomews Hosp, Dept Cardiol, London, England
来源：
IMMUNITY | 2023年 / 56卷 / 06期
关键词：
D O I：
10.1016/j.immuni.2023.05.012
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Neonates are relatively protected from non-neonatal pathogens by unclear mechanisms. In this issue of Immunity, Bee et al.(1) show that resistance to Streptococcus pneumoniae in neonatal mice is mediated by dampened neutrophil efferocytosis, accumulation of aged neutrophils, and enhanced CD11b-dependent bacterial opsonophagocytosis.
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页码：1157 / 1159
页数：3
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