Radiation synthesis of Poly(N-vinylpyrrolidone/acrylic acid/pectin/silver) nanocomposite hydrogel and its antimicrobial activity

被引:0
|
作者
El-Sawy, Naeem M. [1 ]
Fadl, Faten I. Abou El [1 ]
Abdel-Ghaffar, Ashraf M. [1 ]
机构
[1] Egyptian Atom Energy Author, Radiat Res Polymer Chem Dept, Natl Ctr Radiat Res & Technol, Cairo, Egypt
关键词
Gamma radiation; copolymer hydrogel; silver nanoparticles; antibacterial activity; DRUG-DELIVERY; CONTROLLED-RELEASE; POLYMERS; SILVER; PARAMETERS; COPOLYMER; BEHAVIOR; REMOVAL; IONS;
D O I
10.1080/14658011.2021.2015938
中图分类号
TB33 [复合材料];
学科分类号
摘要
Recently, the need for effective antibacterial materials is growing day after day. Hydrogels with antimicrobial activities are strongly recommended in many biomedical applications. This work aims to prepare natural based nanocomposite hydrogel composed of N-vinyl pyrrolidone (NVP), acrylic acid (AAc) and pectin (PEC) embedded with silver nanoparticles (AgNPs). The prepared Poly(NVP/AAc/PEC/Ag) pH-sensitive nanocomposite hydrogel was characterized by gel (%), equilibrium swelling, FTIR, SEM, and XRD. Additionally, in order to confirm the incorporation of AgNPs within the nanocomposite hydrogel matrix during irradiation, TEM analysis was carried out. The AgNPs have average particles size 5.9 +/- 1 nm for 10 kGy, 6.7 nm +/- 2 for 20 kGy, and 8.9 +/- 3 nm for 30 kGy, respectively. The XRD data are in good agreement with TEM analysis. The antibacterial activities of the selected Poly(NVP/AAc/PEC/Ag) nanocomposite hydrogel prepared at 30 kGy irradiation dose towards S. aureus, and E. coli has a higher antibacterial activity than other irradiation doses.
引用
收藏
页码:26 / 36
页数:11
相关论文
共 50 条
  • [11] Synthesis and characterization of poly(N-vinylpyrrolidone) filled by monodispersed silver clusters with controlled size
    Carotenuto, G
    APPLIED ORGANOMETALLIC CHEMISTRY, 2001, 15 (05) : 344 - 351
  • [12] 'Green' synthesis of silver polymer Nanocomposites of poly (2-isopropenyl-2-oxazoline-co- N-vinylpyrrolidone) and its catalytic activity
    Palem, Ramasubba Reddy
    Ganesh, Shimoga D.
    Saha, Nabanita
    Kronek, Juraj
    Saha, Petr
    JOURNAL OF POLYMER RESEARCH, 2018, 25 (07)
  • [13] pH effects in the formation of interpolymer complexes between poly (N-vinylpyrrolidone) and poly(acrylic acid) in aqueous solutions
    Nurkeeva, ZS
    Mun, GA
    Khutoryanskiy, VV
    Bitekenova, AB
    Dubolazov, AV
    Esirkegenova, SZ
    EUROPEAN PHYSICAL JOURNAL E, 2003, 10 (01): : 65 - 68
  • [14] SYNTHESIS OF 6-CROTONOILAMINOCAPROIC ACID AND ITS COPOLYMERS WITH N-VINYLPYRROLIDONE
    Solovskiy, M. V.
    Zakharova, N. V.
    Tarabukina, E. B.
    Borisenko, M. S.
    Vlasova, E. N.
    Alekseeva, P. E.
    IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 2013, 56 (09): : 74 - +
  • [15] pH effects in the formation of interpolymer complexes between poly(N-vinylpyrrolidone) and poly(acrylic acid) in aqueous solutions
    Z.S. Nurkeeva
    G.A. Mun
    V.V. Khutoryanskiy
    A.B. Bitekenova
    A.V. Dubolazov
    S.Zh. Esirkegenova
    The European Physical Journal E, 2003, 10 : 65 - 68
  • [16] Hydrogen bonding and miscibility behavior in poly [ethylene-co-(acrylic acid)] and poly (N-vinylpyrrolidone) mixtures
    Nuño-Donlucas, S
    Puig, J
    Katime, I
    MACROMOLECULAR CHEMISTRY AND PHYSICS, 2001, 202 (16) : 3106 - 3111
  • [17] Radiation synthesis of poly(N-vinyl pyrrolidone\chitosan\itaconic acid\ZnO) nanocomposite hydrogel for antimicrobial activity and controlled release of amoxicillin
    Fadl, Faten I. Abou El
    Ghaffar, Ashraf M. Abdel
    El-Sawy, Naeem M.
    POLYMERS & POLYMER COMPOSITES, 2022, 30
  • [18] Radiation synthesis of poly(N-vinyl pyrrolidone\chitosan\itaconic acid\ZnO) nanocomposite hydrogel for antimicrobial activity and controlled release of amoxicillin
    Abou El Fadl, Faten I.
    Abdel Ghaffar, Ashraf M.
    El-Sawy, Naeem M.
    POLYMERS & POLYMER COMPOSITES, 2022, 30
  • [19] ‘Green’ synthesis of silver polymer Nanocomposites of poly (2-isopropenyl-2- oxazoline-co- N-vinylpyrrolidone) and its catalytic activity
    Ramasubba Reddy Palem
    Shimoga D. Ganesh
    Nabanita Saha
    Juraj Kronek
    Petr Sáha
    Journal of Polymer Research, 2018, 25
  • [20] Electrochemical Synthesis of Silver Nanoparticles in the Presence of Poly(N-vinylpyrrolidone) and the Study of Phase-Transfer
    Li, Qiuhong
    ASIAN JOURNAL OF CHEMISTRY, 2010, 22 (08) : 6210 - 6214