Testing interventions to reduce clinical inertia in the treatment of hypertension: rationale and design of a pragmatic randomized controlled trial

被引:2
|
作者
Haff, Nancy [1 ,2 ]
Sreedhara, Sushama Kattinakere
Wood, Wendy [3 ,4 ]
Yom-Tov, Elad [5 ]
Horn, Daniel M. [2 ,6 ]
Hoover, Melissa [7 ]
Low, Greg [7 ]
Lauffenburger, Julie C. [1 ,2 ]
Chaitoff, Alexander [1 ,2 ]
Russo, Massimiliano [1 ,2 ]
Hanken, Kaitlin [1 ]
Crum, Katherine L. [1 ]
Fontanet, Constance P. [1 ]
Choudhry, Niteesh K. [1 ]
机构
[1] Brigham & Womens Hosp, Ctr Healthcare Delivery Sci C4HDS, Dept Med, Div Pharmacoepidemiol & Pharmacoecon, Boston, MA USA
[2] Harvard Med Sch, Boston, MA USA
[3] Univ Southern Calif, Dept Psychol, Los Angeles, CA USA
[4] Univ Southern Calif, Marshall Sch Business, Los Angeles, CA USA
[5] Microsoft Res, Herzliyya, Israel
[6] Massachusetts Gen Hosp, Dept Med, Boston, MA USA
[7] Massachusetts Gen Hosp, Mass Gen Phys Org, Boston, MA USA
基金
美国国家卫生研究院;
关键词
BLOOD-PRESSURE CONTROL; IMPROVE; CARE; ADHERENCE; RISK; INTENSIFICATION; ASSOCIATION; MEDICATIONS; PHYSICIANS; FEEDBACK;
D O I
10.1016/j.ahj.2023.11.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Clinical inertia, or failure to intensify treatment when indicated, leads to suboptimal blood pressure control. Interventions to overcome inertia and increase antihypertensive prescribing have been modestly successful in part because their effectiveness varies based on characteristics of the provider, the patient, or the provider-patient interaction. Understanding for whom each intervention is most effective could help target interventions and thus increase their impact.Methods This three-arm, randomized trial tests the effectiveness of 2 interventions to reduce clinical inertia in hyperten-sion prescribing compared to usual care. Forty five primary care providers (PCPs) caring for patients with hypertension in need of treatment intensification completed baseline surveys that assessed behavioral traits and were randomized to one of three arms: 1) Pharmacist e-consult, in which a clinical pharmacist provided patient-specific recommendations for hyperten-sion medication management to PCPs in advance of upcoming visits, 2) Social norming dashboards that displayed PCP's hypertension control rates compared to those of their peers, or 3) Usual care (no intervention). The primary outcome was the rate of intensification of hypertension treatment. We will compare this outcome between study arms and then evaluate the association between characteristics of providers, patients, their clinical interactions, and intervention responsiveness.Results Forty-five primary care providers were enrolled and randomized: 16 providers and 173 patients in the social norming dashboards arm, 15 providers and 143 patients in the pharmacist e-consult arm, and 14 providers and 150 patients in the usual care arm. On average, the mean patient age was 64 years, 47% were female, and 73% were white. Baseline demographic and clinical characteristics of patients were similar across arms, with the exception of more Hispanic patients in the usual care arm and fewest in the pharmacist e-consult arm. Conclusions This study can help identify interventions to reduce inertia in hypertension care and potentially identify the characteristics of patients, providers, or patient-provider interactions to understand for whom each intervention would be most beneficial.Trial Registration Clinicaltrials.gov (NCT, Registered: NCT04603560) (Am Heart J 2024
引用
收藏
页码:18 / 28
页数:11
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