Alopecia areata incognito: an elusive disease

被引:1
|
作者
Arshdeep, Arshdeep [1 ,3 ]
Batrani, Meenakshi [1 ,2 ]
Kubba, Asha [1 ,2 ]
Kubba, Raj [1 ]
机构
[1] Delhi Dermatol Grp, New Delhi, India
[2] Delhi Dermpath Lab, New Delhi, India
[3] Delhi Dermatol Grp, 10 Aradhana Enclave, New Delhi 110066, India
关键词
ANDROGENETIC ALOPECIA; SCALP DERMOSCOPY; ACUTE DIFFUSE; FEMALE SCALP; HAIR; DIAGNOSIS; CLUE;
D O I
10.1111/ijd.16923
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BackgroundAlopecia areata incognito (AAI) is an under-recognized variant of alopecia areata (AA) that can easily be misdiagnosed as telogen effluvium (TE) or androgenetic alopecia (AGA). Trichoscopy and histopathology studies in AAI are very few, and this disease entity merits wider recognition.ObjectiveThis is a case series of 30 patients of AAI from India, analyzing the clinical, trichoscopic, and histological features.MethodsA total of 30 patients, 19 females and 11 males of mean age 32.3 +/- 10.5 years, diagnosed with AAI from January 2019 to January 2022 were studied retrospectively. Trichoscopy was performed in all 30 cases. Trichoscopy-guided biopsy was done in 15 consenting patients. Transverse sections were studied for hair counts, ratios, and morphological features.ResultsDiffuse hair thinning was noted, with 73% of patients showing predominant involvement of androgen-dependent scalp. Trichoscopy showed multiple yellow dots, short regrowing hair, and empty follicles. Circle hair or pigtail hair was noted in 77% of patients. Discrete black dots and exclamation-mark hair were seen in only six (20%). The most striking feature on histopathology was the presence of nanogen hairs (miniaturized non-anagen, anagen-like, telogen germ units, or indeterminate hairs) with a mean count of 34%, marking a shift toward telogen in mean anagen:telogen ratio of 1.3:1. Dilated infundibula and subtle peribulbar inflammatory infiltrate around miniaturized follicles and fibrous stellae were observed.ConclusionTrichoscopy-histopathology correlation helps to diagnose AAI and differentiate it from TE or AGA. This would help a clinician to provide better outcomes in hair regrowth.
引用
收藏
页码:316 / 321
页数:6
相关论文
共 50 条
  • [21] Screening of Celiac Disease in Children with Alopecia Areata
    Ertekin, Vildan
    Tosun, Mahya Sultan
    Erdem, Teoman
    INDIAN JOURNAL OF DERMATOLOGY, 2014, 59 (03)
  • [22] ALOPECIA-AREATA - A DISEASE OF CORTICAL DIFFERENTIATION
    MESSENGER, AG
    SLATER, DN
    BLEEHEN, SS
    BRITISH JOURNAL OF DERMATOLOGY, 1983, 109 : 36 - 36
  • [23] The global burden of disease associated with alopecia areata
    Karimkhani, C.
    Boyers, L. N.
    Naghavi, M.
    Coffeng, L. E.
    Lott, J. P.
    Wulf, S.
    Hay, R.
    Williams, H. C.
    Weinstock, M. A.
    Norton, S. A.
    Armstrong, A. W.
    Dunnick, C. A.
    Norris, D. A.
    Dellavalle, R. P.
    BRITISH JOURNAL OF DERMATOLOGY, 2015, 172 (05) : 1424 - 1426
  • [24] SCREENING OF CELIAC DISEASE IN CHILDREN WITH ALOPECIA AREATA
    Ertekin, V.
    Tosun, M. S.
    Erdem, T.
    JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2010, 50 : E64 - E64
  • [25] Alopecia Areata in an Adolescent With Inflammatory Bowel Disease
    Sankararaman, Senthilkumar
    Bobonich, Margaret
    Aktay, Atiye Nur
    CLINICAL PEDIATRICS, 2017, 56 (14) : 1350 - 1352
  • [26] Alopecia areata
    Hoffmann, R
    Happle, R
    HAUTARZT, 1999, 50 (03): : 222 - 231
  • [27] Alopecia areata
    Marta Bujan, Maria
    Bocian, Marcela
    Bettina Cervini, Andrea
    Martin Pierini, Adrian
    ARCHIVOS ARGENTINOS DE PEDIATRIA, 2013, 111 (05): : 455 - 456
  • [28] Alopecia areata
    Montazeri, A
    Serre, G
    Kanitakis, J
    EUROPEAN JOURNAL OF DERMATOLOGY, 1996, 6 (07) : 471 - 478
  • [29] ALOPECIA AREATA
    不详
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1955, 158 (13): : 1237 - 1237
  • [30] ALOPECIA AREATA
    TALBOTT, JH
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1963, 186 (07): : 721 - &