Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen

被引:0
|
作者
Miyamura, Shogo [1 ]
Oe, Ryo [1 ]
Nakahara, Takuya [1 ]
Taue, Shuji [1 ]
Tokizane, Yu [1 ]
Minamikawa, Takeo [1 ]
Kajisa, Taira [1 ]
Yasui, Takeshi [1 ]
机构
[1] Tokushima Univ, Inst Post LED Photon pLED, 2-1 Minami Josanjima, Tokushima 7708506, Japan
关键词
Optical comb; biosensing; COVID-19; SARS-VoV-2;
D O I
10.1117/12.2651247
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
One interesting feature of optical frequency comb (OFC) is a function of frequency conversion between region and electric regions. While such feature has been used for generation of correct electric signal in microwave or millimeter region, it can be further used for fiber biosensing; namely, biosensing OFC. In this paper, we demonstrated detection of SARS-CoV-2 antigen based on a combination of dual fiber combs, an intracavity multi-mode-interference fiber sensor, and sensor surface modification of SARS-CoV-2 antibody.
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页数:3
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