Single-cell analysis of the long noncoding RNA transcriptome in cardiac fibroblasts reveals FIXER as a novel therapeutic target for fibrosis in the injured heart

被引：0
|
作者：
Aghagolzadeh, P. [1 ]
Plaisance, I. [1 ]
Bernasconi, R. [2 ]
Treibel, T. A. [3 ]
Quetglas, C. P. [4 ]
Wyss, T. [5 ]
Nemir, M. [1 ]
Sarre, A. [1 ]
Chouvardas, P. [4 ]
Johnson, R. [4 ]
Gonzalez, A. [6 ]
Pedrazzini, P. [1 ]
机构：
[1] Univ Lausanne Hosp, Lausanne, Switzerland
[2] Univ Basel, Basel, Switzerland
[3] UCL, London, England
[4] Univ Hosp Bern, Inselspital, Bern, Switzerland
[5] Swiss Inst Bioinformat, Lausanne, Switzerland
[6] Appl Med Res Ctr CIMA, Pamplona, Spain
来源：
EUROPEAN JOURNAL OF HEART FAILURE | 2023年 / 25卷
基金：
瑞士国家科学基金会;
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
11
引用
收藏
页码：12 / 12
页数：1
相关论文
共 50 条
  • [41] Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts
    Wang, Yi
    Chen, Guihua
    Li, Deng
    BIOLOGY DIRECT, 2024, 19 (01)
  • [42] Single-cell RNA sequencing reveals the transcriptional heterogeneity of Tbx18-positive cardiac cells during heart development
    Xianglin Long
    Jiangjun Wei
    Qinghua Fang
    Xin Yuan
    Jianlin Du
    Functional & Integrative Genomics, 2024, 24
  • [43] Single-cell RNA sequencing reveals the transcriptional heterogeneity of Tbx18-positive cardiac cells during heart development
    Long, Xianglin
    Wei, Jiangjun
    Fang, Qinghua
    Yuan, Xin
    Du, Jianlin
    FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 24 (01)
  • [44] Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury
    Cortada, Eric
    Yao, Jun
    Xia, Yu
    Duendar, Friederike
    Zumbo, Paul
    Yang, Boris
    Rubio-Navarro, Alfonso
    Perder, Bjoern
    Qiu, Miaoyan
    Pettinato, Anthony M.
    Homan, Edwin A.
    Stoll, Lisa
    Betel, Doron
    Cao, Jingli
    Lo, James C.
    COMMUNICATIONS BIOLOGY, 2024, 7 (01)
  • [45] Single-cell transcriptome analysis revealed heterogeneity in glycolysis and identified IGF2 as a therapeutic target for ovarian cancer subtypes
    Ji, Jinting
    Bi, Fangfang
    Zhang, Xiaocui
    Zhang, Zhiming
    Xie, Yichi
    Yang, Qing
    BMC CANCER, 2024, 24 (01)
  • [46] Single-cell RNA-seq analysis reveals ploidy-dependent and cell-specific transcriptome changes in Arabidopsis female gametophytes
    Qingxin Song
    Atsumi Ando
    Ning Jiang
    Yoko Ikeda
    Z. Jeffrey Chen
    Genome Biology, 21
  • [47] Single-cell RNA-seq analysis reveals ploidy-dependent and cell-specific transcriptome changes in Arabidopsis female gametophytes
    Song, Qingxin
    Ando, Atsumi
    Jiang, Ning
    Ikeda, Yoko
    Chen, Z. Jeffrey
    GENOME BIOLOGY, 2020, 21 (01)
  • [48] Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia
    Sun, Hao
    Liu, Xia
    Guerrera, Maria Luisa
    Tsakmaklis, Nickolas
    Kofides, Amanda
    Gamero, Andres Felipe Ramirez
    Flynn, Catherine A.
    Patterson, Christopher J.
    Hao, Mu
    Qiu, Lugui
    Sarosiek, Shayna R.
    Castillo, Jorge J.
    Hunter, Zachary R.
    Liu, Shirong
    Treon, Steven P.
    BLOOD, 2024, 144 : 743 - 744
  • [49] Single-Cell RNA Sequencing Reveals Keratinocytes and Fibroblasts Drive Hippo and TGFb Dysregulation and Fibrosis in Epidermal Overexpression of VGLL3 in Cutaneous Lupus
    Gharaee-Kermani, Mehrnaz
    Billi, Allison
    Martens, Jacob
    Hildebrandt, Marisa
    Victory, Amanda
    Maz, Mitra
    Loftus, Shannon
    Kahlenberg, J. Michelle
    Gudjonsson, Johann E.
    ARTHRITIS & RHEUMATOLOGY, 2023, 75 : 1777 - 1779
  • [50] Integrative single-cell transcriptome analysis provides new insights into post-COVID-19 pulmonary fibrosis and potential therapeutic targets
    Kim, Yumin
    Kim, Yeongmin
    Lim, Hyobin Julianne
    Kim, Dae-Kyum
    Park, Ji-Hwan
    Oh, Chang-Myung
    JOURNAL OF MEDICAL VIROLOGY, 2023, 95 (11)
12345