EFFICACY AND SAFETY OF UPADACITINIB IN TNFI INADEQUATE RESPONDERS WITH RHEUMATOID ARTHRITIS FROM THREE PHASE 3 CLINICAL TRIALS

被引：0
|
作者：
Fleischmann, Roy [1 ]
Bessette, Louis [2 ]
Hall, Stephen [3 ,4 ]
Sparks, Jeffrey [5 ]
Jain, Manish [6 ]
Kakehasi, Adriana [7 ]
Song, Yanna [8 ]
Meerwein, Sebastian [8 ]
DeMasi, Ryan [8 ]
Suboticki, Jessica [8 ]
Rubbert-Roth, Andrea [9 ]
机构：
[1] Metroplex Clin Res Ctr, Rheumatol, Dallas, TX USA
[2] Laval Univ, Div Rheumatol, Dept Med, Quebec City, PQ, Canada
[3] Monash Univ, Rheumatol, Melbourne, Australia
[4] Emeritus Res, Melbourne, Australia
[5] Brigham & Womens Hosp, Div Rheumatol Inflammat & Immun, Boston, MA USA
[6] Great Lakes Clin Trials, Rheumatol, Chicago, IL USA
[7] Univ Fed Minas Gerais, Hosp Clin, Rheumatol, Belo Horizonte, Brazil
[8] AbbVie Inc, Immunol, Chicago, IL USA
[9] Cantonal Clin St Gallen, Div Rheumatol, St Gallen, Switzerland
来源：
RHEUMATOLOGY | 2023年 / 62卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P135
引用
收藏
页数：2
相关论文
共 50 条
  • [21] EXPOSURE-RESPONSE ANALYSES OF UPADACITINIB EFFICACY AND SAFETY IN RHEUMATOID ARTHRITIS - ANALYSES OF PHASE 2 AND 3 STUDIES
    Mohamed, Mohamed-Eslam
    Nader, Ahmed
    Winzenborg, Insa
    Doelger, Eva
    Noertersheuser, Peter
    Pangan, Aileen
    Othman, Ahmed
    ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 739 - 740
  • [22] Safety of upadacitinib in Latin American patients with rheumatoid arthritis: an integrated safety analysis of the SELECT phase 3 clinical program
    Kakehasi, Adriana Maria
    Radominski, Sebastiao Cezar
    Baravalle, Marcos Daniel
    Palazuelos, Fedra Consuelo Irazoque
    Garcia-Garcia, Conrado
    Arruda, Maysa Silva
    Curi, Marco
    Liu, John
    Qiao, Meihua
    Velez-Sanchez, Patricia
    Vargas, Juan Ignacio
    CLINICAL RHEUMATOLOGY, 2023, 42 (05) : 1249 - 1258
  • [23] Pharmacokinetics of Upadacitinib With the Clinical Regimens of the Extended-Release Formulation Utilized in Rheumatoid Arthritis Phase 3 Trials
    Mohamed, Mohamed-Eslam F.
    Zeng, Jiewei
    Marroum, Patrick J.
    Song, In-Ho
    Othman, Ahmed A.
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2019, 8 (02): : 208 - 216
  • [24] Evaluating the efficacy of upadacitinib in patients with moderate rheumatoid arthritis: a post-hoc analysis of the SELECT phase 3 trials
    Conaghan, Philip G.
    Pavelka, Karel
    Hsieh, Song-Chou
    Bonnington, Terri-Leigh
    Kent, Toby C.
    Marchbank, Katie
    Edwards, Christopher J.
    RHEUMATOLOGY ADVANCES IN PRACTICE, 2022, 7 (01)
  • [25] EFFICACY OF UPADACITINIB IN RHEUMATOID ARTHRITIS PATIENTS WITH INADEQUATE RESPONSE TO FIRST GENERATION JAK INHIBITORS
    Kamiya, M.
    Mori, S.
    Yamazaki, K.
    Togawa, D.
    ANNALS OF THE RHEUMATIC DISEASES, 2024, 83
  • [26] Long-Term Safety and Efficacy of Upadacitinib in Patients with Rheumatoid Arthritis and an Inadequate Response to CsDMARDs: Results at 60 Weeks
    Burmester, Gerd
    Van den Bosch, Filip
    Bessette, Louis
    Kivitz, Alan
    Li, Yihan
    Friedman, Alan
    Pangan, Aileen
    Camp, Heidi
    Kremer, Joel
    ARTHRITIS & RHEUMATOLOGY, 2019, 71
  • [27] EFFICACY AND SAFETY OF SARILUMAB IN COMBINATION WITH CSDMARDS IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS WHO WERE INADEQUATE RESPONDERS OR INTOLERANT OF ANTI-TNF-α THERAPY: RESULTS FROM A PHASE 3 STUDY
    Fleischmann, Roy
    Pinheiro Geraldo Da, R. C.
    Anie Brzezicki, J.
    Hrycaj, Pawel
    Lin, Yong
    Van Adelsberg, Janet
    Graham, Neil
    Van Hoogstraten, Hubert
    Bauer, Deborah
    Burmester Gerd, R.
    INTERNAL MEDICINE JOURNAL, 2016, 46 : 41 - 41
  • [28] SAFETY OF LEFLUNOMIDE IN RHEUMATOID ARTHRITIS; FROM CLINICAL TRIALS TO CLINICAL PRACTICE
    Hassan, Al
    Galarraga, B.
    Jordan, K. M.
    Armstrong, R. D.
    RHEUMATOLOGY, 2003, 42 : 98 - 98
  • [29] Upadacitinib pharmacokinetics and exposure-response analyses of efficacy and safety in psoriatic arthritis patients - Analyses of phase III clinical trials
    Muensterman, Elena
    Engelhardt, Benjamin
    Gopalakrishnan, Sathej
    Anderson, Jaclyn K.
    Mohamed, Mohamed-Eslam F.
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2022, 15 (01): : 267 - 278
  • [30] Effect of BMI on Baricitinib Efficacy: Pooled Analysis from Two Phase 3 Rheumatoid Arthritis Clinical Trials
    Zerbini, Cristiano A. F.
    Muram, David
    Arora, Vipin K.
    Alam, Jahangir
    Curtis, Jeffrey R.
    ARTHRITIS & RHEUMATOLOGY, 2016, 68
12345