Fas ligand intracellular signaling: does PSTPIP mediate T cell death?

被引：0

作者：

Silva, Rafael Cardoso Maciel Costa ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Lab Immunoreceptors & Signaling, Inst Biofis Carlos Chagas Filho, Rio de Janeiro, Brazil

来源：

APOPTOSIS | 2024年 / 29卷 / 1-2期

关键词：

Fas; FasL; cell death; Lymphoproliferative diseases;

D O I：

10.1007/s10495-023-01892-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fas and Fas ligand (FasL)-induced cell death is critical for the appropriate regulation of immune responses, especially those mediated by T cells. In this letter, several studies are discussed that reinforce the importance of FasL intracellular signaling for CD4 + T cell death, which might involve PSTPIP phosphatase and/or MAPKs.

引用

页码：1 / 2

页数：2

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