Fas ligand intracellular signaling: does PSTPIP mediate T cell death?

被引：0
|
作者：
Silva, Rafael Cardoso Maciel Costa [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Lab Immunoreceptors & Signaling, Inst Biofis Carlos Chagas Filho, Rio de Janeiro, Brazil
来源：
APOPTOSIS | 2024年 / 29卷 / 1-2期
关键词：
Fas; FasL; cell death; Lymphoproliferative diseases;
D O I：
10.1007/s10495-023-01892-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Fas and Fas ligand (FasL)-induced cell death is critical for the appropriate regulation of immune responses, especially those mediated by T cells. In this letter, several studies are discussed that reinforce the importance of FasL intracellular signaling for CD4 + T cell death, which might involve PSTPIP phosphatase and/or MAPKs.
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页码：1 / 2
页数：2
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