Fenfluramine Treatment Is Associated With Improvement in Everyday Executive Function in Adults With Lennox-Gastaut Syndrome: Post-Hoc Analysis of Dose Effects From a Phase 3 Trial Rationale

被引：5

作者：

Bishop, Kim ^{[1
]}

Isquith, Peter ^{[1
,2
]}

Knupp, Kelly ^{[3
]}

Sullivan, Joseph ^{[4
]}

Nabbout, Rima ^{[5
]}

Gil-Nagel, Antonio ^{[6
]}

Scheffer, Ingrid ^{[7
,8
,9
]}

Auvin, Stephane ^{[10
]}

Cross, J. Helen ^{[11
]}

Guerrini, Renzo ^{[12
]}

Roth, Robert ^{[1
,13
]}

Gioia, Gerard ^{[1
,14
]}

Lothe, Amelie ^{[15
]}

Polega, Shikha ^{[16
]}

机构：

[1] Global Pharma Consultancy LLC, Muncy, PA USA

[2] Harvard Med Sch, Boston Childrens Hosp, Boston, MA USA

[3] Childrens Hosp Colorado, Aurora, CO USA

[4] Univ Calif San Francisco, Benioff Childrens Hosp, San Francisco, CA USA

[5] Univ Paris Cite, Hop Univ Necker Enfants Malad, APHP, Reference Ctr Rare Epilepsies,Inst Imagine,EPICAR, Paris, France

[6] Hosp Ruber Int, Madrid, Spain

[7] Univ Melbourne, Austin Hosp, Heidelberg, Vic, Australia

[8] Royal Childrens Hosp, Florey Inst, Parkville, Vic, Australia

[9] Murdoch Childrens Res Inst, Murdoch, WA, Australia

[10] Univ Paris, Robert Debre Univ Hosp, APHP, Inst Univ France IUF, Paris, France

[11] UCL NIHR BRC Great Ormond St Inst Child Hlth, London, England

[12] Univ Florence, Anna Meyer Childrens Hosp, Florence, Italy

[13] Dartmouth Hitchcock Med Ctr, Lebanon, NH USA

[14] Childrens Natl Hlth Syst, Washington, DC USA

[15] Zogenix Int, Maidenhead, England

[16] Zogenix Inc, Emeryville, CA USA

来源：

NEUROLOGY | 2023年 / 100卷 / 17期

关键词：

D O I：

10.1212/WNL.0000000000202479

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

P11-1.001

引用

页数：6

共 25 条

[21] Radiographic Outcomes Were Associated with Pain and Function Responses: Post-Hoc Analysis of Results from a Phase 2 Study of a Small Molecule Wnt Pathway Inhibitor, SM04690, for Knee Osteoarthritis Treatment
Yazici, Yusuf
McAlindon, Timothy E.
Gibofsky, Allan
Lane, Nancy E.
Skrepnik, Nebojsa
Armas, Eddie
Swearingen, Christopher J.
DiFrancesco, Anita
Tambiah, Jeymi
Hochberg, Marc
ARTHRITIS & RHEUMATOLOGY, 2017, 69
[22] A post-hoc subgroup analysis in participants with migraine with aura from the TEAM (a phase 3 randomized, double-blind, sham- controlled Trial of e-TNS for the Acute treatment of Migraine) study
Kuruvilla, D.
Panza, G.
Johnson, M.
HEADACHE, 2023, 63 : 115 - 116
[23] Effects of Linaclotide on Straining Associated With Bowel Movements in Patients With Irritable Bowel Syndrome With Constipation (IBS-C): A Post Hoc Analysis of Pooled Data From Two Phase 3 Trials
Lembo, Anthony
Rao, Satish S.
Shiff, Steven J.
Lavins, Bernard J.
MacDougall, James E.
Shi, Kelvin
Schneier, Harvey
Currie, Mark G.
Johnston, Jeffrey M.
GASTROENTEROLOGY, 2012, 142 (05) : S828 - S829
[24] A post hoc analysis of migraine-associated symptoms from the phase 3 randomized, double-blind, sham-controlled Trial of External trigeminal nerve stimulation for the Acute treatment of Migraine (TEAM) study
Panza, Gregory A.
Johnson, Michael A. L.
Kuruvilla, Deena E.
HEADACHE, 2024,
[25] Potential of Tenapanor as a Treatment for Chronic Idiopathic Constipation (CIC): A Post Hoc Analysis From the T3MPO-1 and T3MPO-2 Phase 3 Studies for Irritable Bowel Syndrome With Constipation (IBS-C) in Adults
Harris, Lucinda A.
Rosenbaum, David P.
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2022, 117 (10): : S393 - S393

← 1 2 3 →