ITGAL as a prognostic biomarker correlated with immune infiltrates in melanoma

被引：2
|
作者：
Deng, TengFei [1 ]
Wang, Chaoyong [2 ]
Gao, Cong [1 ]
Zhang, Qiang [1 ]
Guo, Jun [1 ]
机构：
[1] Yangzhou Univ, Plast Surg Dept, Affiliated Hosp, Yangzhou, Peoples R China
[2] Yangzhou Univ, Med Coll, Yangzhou, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2023年 / 13卷
关键词：
ITGAL; melanoma; prognostic biomarker; immune infiltrates; MIHC; CELLS; ACTIVATION; ADHESION; CD4(+); CANCER; ICAM-1;
D O I：
10.3389/fonc.2023.1181537
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This study investigates the relationship between ITGAL expression and immune infiltration, clinical prognosis, and specific types of T cells in melanoma tissue. The findings reveal the key role of ITGAL in melanoma and its potential mechanism of regulating tumor immune infiltrating cells, highlighting its potential as a diagnostic biomarker and therapeutic target for advanced melanoma.
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页数：14
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