Constituents from the Polar Extract of Pisolithus arhizus and Their Anti-inflammatory Activity

被引：1

作者：

Parisi, Valentina ^{[1
]}

Nocera, Raffaella ^{[1
]}

Rosa, Emanuele ^{[1
]}

Iobbi, Valeria ^{[2
]}

Ebrahimi, Samad Nejad ^{[3
]}

Braca, Alessandra ^{[4
]}

De Tommasi, Nunziatina ^{[1
]}

Donadio, Giuliana ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Farm, I-84084 Fisciano, SA, Italy

[2] Univ Genoa, Dipartimento Farm, I-16148 Genoa, Italy

[3] Shahid Beheshti Univ, Med Plants & Drugs Res Inst, Dept Phytochem, Tehran 1983969411, Iran

[4] Univ Pisa, Dipartimento Farm, I-56126 Pisa, Italy

来源：

JOURNAL OF NATURAL PRODUCTS | 2024年 / 87卷 / 03期

关键词：

NAPHTHALENOID PULVINIC ACID; EARLY STEPS; TRITERPENOIDS; FUNGI;

D O I：

10.1021/acs.jnatprod.3c01055

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The phytochemical study of the Pisolithus arhizus fruiting body methanol extract led to the isolation of six new triterpenoids (1-6) and one new naphthalenoid pulvinic acid derivative (7), together with five known compounds, including norbadione A (8). Their structure was established from 1D and 2D NMR spectroscopy and HRESIMS analyses. The absolute configuration of the triterpenoids was determined by circular dichroism. The two pulvinic acid derivatives 7 and 8, showing the highest activity in modulating IL-6 secretion, were tested for their effect on COX-2, STAT3, and p-STAT3 proteins; both compounds were able to downregulate p-STAT3.

引用

页码：520 / 529

页数：10

共 50 条

[41] Anti-inflammatory activity of extract and fractions from Nepeta sibthorpii Bentham
Miceli, N
Taviano, MF
Giuffrida, D
Trovato, A
Tzakou, O
Galati, EM
JOURNAL OF ETHNOPHARMACOLOGY, 2005, 97 (02) : 261 - 266
[42] Anti-inflammatory Activity of Polyphenols from Labisia pumila Leaves Extract
Hassan, Sharifah Norzi Syed
Hasham, Rosnani
Hashim, Siti Hajar
Hamzah, Mohd Amir Asyraf Mohd
MALAYSIAN JOURNAL OF FUNDAMENTAL AND APPLIED SCIENCES, 2024, 20 (02): : 482 - 496
[43] Anti-inflammatory activity of the aqueous extract from Rhizoma smilacis glabrae
Jiang, JY
Wu, FH
Lu, JF
Lu, ZH
Xu, Q
PHARMACOLOGICAL RESEARCH, 1997, 36 (04) : 309 - 314
[44] Three new constituents from the fungus of Monascus purpureus and their anti-inflammatory activity
Wu, Ho-Cheng
Cheng, Ming-Jen
Wu, Ming-Der
Chen, Jih-Jung
Chen, Yen-Lin
Chang, Hsun-Shuo
PHYTOCHEMISTRY LETTERS, 2019, 31 : 242 - 248
[45] Chemical constituents from the stem bark of Illicium burmanicum and their anti-inflammatory activity
Li, Chuntong
Xu, Deduo
Zheng, Zhancai
Lu, Wenquan
Yang, Yingbo
Chen, Wansheng
Wu, Zhijun
PHYTOCHEMISTRY, 2025, 229
[46] A new polyacetylene and other constituents with anti-inflammatory activity from Artemisia halodendron
Jin, Long
Zhou, Wei
Li, Ren
Jin, Mei
Jin, Chunshi
Sun, Jinfeng
Li, Gao
NATURAL PRODUCT RESEARCH, 2021, 35 (06) : 1010 - 1013
[47] Isolation of chemical constituents with anti-inflammatory activity from Reineckia carnea herbs
Xu, Xu
Tan, Ting
Zhang, Jing
Li, Zhi-Feng
Yang, Shi-Lin
Wen, Quan
Feng, Yu-Lin
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2020, 22 (04) : 303 - 315
[48] Phenolic Constituents from the Twigs of Euonymus alatus and Their Cytotoxic and Anti-inflammatory Activity
Kim, Ki Hyun
Ha, Sang Keun
Choi, Sang Un
Kim, Sun Yeou
Lee, Kang Ro
PLANTA MEDICA, 2013, 79 (05) : 361 - 364
[49] Anti-inflammatory activity of constituents from Glechoma hederacea var. longituba
Kim, JinPyo
Song, SeokBean
Lee, IkSoo
Kim, YoungHo
Yoo, IckDong
Ryoo, InJa
Bae, KiHwan
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (11) : 3483 - 3487
[50] Novel chemical constituents with anti-inflammatory activity from the leaves of Sesbania aculeata
Sharma, Shelly
Chattopadhyay, Sunil K.
Singh, Monika
Bawankule, Dnyaneshwar U.
Kumar, Satyanshu
PHYTOCHEMISTRY, 2014, 100 : 132 - 140

← 1 2 3 4 5 →