Microwave-promoted multi-component and green synthesis of thiadiazolo[3,2-a]pyrimidines under solvent-free conditions

被引：0
|
作者：
Pouramiri, Behjat [1 ]
Rashidi, Mohsen [2 ]
机构：
[1] Qom Univ Technol, Dept Organ Chem, Qom 37195, Iran
[2] Shahid Bahonar Univ Kerman, Fac Sci, Dept Chem, Kerman 76169, Iran
来源：
JOURNAL OF CHEMICAL SCIENCES | 2023年 / 135卷 / 03期
关键词：
Multi-component reaction (MCRs); microwave irradiation; thiadiazolo[2,3-a]pyrimidines; green synthesis; IONIC LIQUIDS; ONE-POT; DERIVATIVES;
D O I：
10.1007/s12039-023-02217-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This research is aimed at synthesizing pyrimidine heterocycles that contain 1,3,4-thiadiazole ring moiety by microwave-assisted multi-component reactions. For this purpose, synthesizing of [1,3,4] thiadiazolo[3,2-a]pyrimidine-6-carboxylate derivatives was carried out in a single-step reaction using aromatic aldehydes, ethyl acetoacetate, and different derivatives of 1,3,4-thiadiazoles (with molar ratio of 1:2:1 respectively) in the presence of [Et3NH]+[HSO4]- ionic liquid, under solvent-free conditions.Graphical abstractThis research, synthesis of [1,3,4] thiadiazolo[3,2-a]pyrimidine-6-carboxylate derivatives was carried out in a single-step reaction using aromatic aldehydes, ethyl acetoacetate and different derivatives of 1,3,4-thiadiazoles (with molar ratio of 1:2:1, respectively) in the presence of [Et3NH]+[HSO4]- ionic liquid under solvent-free microwave irradiation.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Microwave-promoted multi-component and green synthesis of thiadiazolo[3,2-a]pyrimidines under solvent-free conditions
    Behjat Pouramiri
    Mohsen Rashidi
    Journal of Chemical Sciences, 135
  • [2] Ionic-liquid Promoted Multi-component Preparation of Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidines under Solvent-free Conditions
    Ziyaadini, Morteza
    Roudbaraki, Seyyed Jalal
    Ghashang, Majid
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2020, 52 (04) : 311 - 318
  • [3] Multi-component Preparation of Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidines Using Solvent-free and HSBM Techniques
    Roudbaraki, Seyyed Jalal
    Ziyaadini, Morteza
    Ghashang, Majid
    LETTERS IN ORGANIC CHEMISTRY, 2020, 17 (07) : 512 - 516
  • [4] Regioselective, Solvent-Free Synthesis of 3-Aminoimidazo[1,2-a]pyrimidines Under Microwave Irradiation Promoted by Zeolite HY
    Thompson, Mark J.
    Hurst, Jenny M.
    Chen, Beining
    SYNLETT, 2008, (20) : 3183 - 3187
  • [5] Rapid microwave-promoted solvent-free synthesis of hypervalent iodine reagents
    Zhou, Zhongshi
    He, Xuehan
    JOURNAL OF CHEMICAL RESEARCH-S, 2009, (01): : 30 - 31
  • [6] Microwave-Promoted Michael Addition of Azaheterocycles to α,β-Unsaturated Esters and Acid under Solvent-Free Conditions
    Dubois, Lilian
    Acher, Francine C.
    McCort-Tranchepain, Isabelle
    SYNLETT, 2012, (05) : 791 - 795
  • [7] Microwave-promoted efficient synthesis of pyrano[3,2-c]chromen-5(4H)-ones under catalyst and solvent-free conditions
    Reddy, Mudumala Veeranarayana
    Kumar, Badur Siva
    Lim, Kwon Taek
    Cho, Byung Gwon
    Jeong, Yeon Tae
    TETRAHEDRON LETTERS, 2016, 57 (04) : 476 - 478
  • [8] Multi-component synthesis of pyran-annulated thiazoles under solvent-free microwave irradiation
    Yadav, LDS
    Singh, A
    SYNTHESIS-STUTTGART, 2003, (15): : 2395 - 2399
  • [9] Microwave-mediated regioselective synthesis of novel pyrimido[1,2-a]pyrimidines under solvent-free conditions
    Vanden Eynde, JJ
    Hecq, N
    Kataeva, O
    Kappe, CO
    TETRAHEDRON, 2001, 57 (09) : 1785 - 1791
  • [10] An efficient microwave-promoted three-component synthesis of thiazolo[3,2-a]pyrimidines catalyzed by SiO2-ZnBr2 and antimicrobial activity evaluation
    Devineni, Subba Rao
    Madduri, Thirupal Reddy
    Chamarthi, Naga Raju
    Liu, Cong-Qiang
    Pavuluri, Chandra Mouli
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2019, 55 (03) : 266 - 274
12345