A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab

被引:0
|
作者
Kurokawa, Masahiro [1 ,2 ]
Ikarashi, Daiki [1 ]
Kato, Renpei [1 ]
Kanehira, Mitsugu [1 ]
Fukagai, Takashi [2 ]
Obara, Wataru [1 ]
机构
[1] Iwate Med Univ, Dept Urol, Sch Med, 2-1-1 Idaidori,Yahaba Cho, Morioka, Iwate 0283695, Japan
[2] Showa Univ, Sch Med, Dept Urol, Tokyo, Japan
关键词
Pembrolizumab; Lenvatinib; Renal cell carcinoma; Inferior vena cava thrombus; Pancreatitis;
D O I
10.1007/s13691-024-00657-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pancreatic injury is a rare, but noted complication of nephrectomy. We report a case involving a 56-year-old man who presented with cT3bN0M0 left locally advanced renal cell carcinoma with an inferior vena cava thrombus. Nephrectomy with thrombectomy was performed given the remarkable shrinkage of the primary tumor and thrombus following lenvatinib plus pembrolizumab administration. The patient developed postoperative pancreatitis associated with unrecognized minor pancreatic injury, which was treated conservatively. To our knowledge, this has been the first case that underwent nephrectomy for RCC with an IVC thrombus after presurgical lenvatinib plus pembrolizumab and received conservative treatment for postoperative pancreatitis.
引用
收藏
页码:158 / 161
页数:4
相关论文
共 50 条
  • [21] Surgical Management of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus
    Dason, Shawn
    Mohebali, Jahan
    Blute Sr, Michael L.
    Salari, Keyan
    UROLOGIC CLINICS OF NORTH AMERICA, 2023, 50 (02) : 261 - 284
  • [22] Remarkable effect of presurgical nivolumab on originally inoperable papillary renal cell carcinoma with tumor thrombus in inferior vena cava
    Shinagawa, Tomochika
    Ito, Hideaki
    Sakai, Yasuhiro
    Mikami, Shuji
    Oe, Hideki
    Taga, Minekatsu
    Yokoyama, Osamu
    INTERNATIONAL CANCER CONFERENCE JOURNAL, 2019, 8 (04) : 170 - 174
  • [23] The efficacy and safety of presurgical therapy with tislelizumab and axitinib for renal cell carcinoma with inferior vena cava tumor thrombus.
    Wang, Xuegang
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [24] Remarkable effect of presurgical nivolumab on originally inoperable papillary renal cell carcinoma with tumor thrombus in inferior vena cava
    Tomochika Shinagawa
    Hideaki Ito
    Yasuhiro Sakai
    Shuji Mikami
    Hideki Oe
    Minekatsu Taga
    Osamu Yokoyama
    International Cancer Conference Journal, 2019, 8 : 170 - 174
  • [25] PRESURGICAL TREATMENT WITH PAZOPANIB IMPROVED SURGICAL OUTCOME OF ADVANCED RENAL CELL CARCINOMA WITH INFERIOR VENA CAVA TUMOR THROMBUS
    Okamura, Yasuyoshi
    Sakamoto, Mariko
    Bando, Yukari
    Suzuki, Kotaro
    Hara, Takuto
    Terakawa, Tomoaki
    Furukawa, Jyunya
    Harada, Kenichi
    Hinata, Nobuykuki
    Nakano, Yuzo
    Fujisawa, Masato
    JOURNAL OF UROLOGY, 2019, 201 (04): : E343 - E343
  • [26] Presurgical axitinib therapy increases fibrotic reactions within tumor thrombus in renal cell carcinoma with thrombus extending to the inferior vena cava
    Tanaka, Yoshimi
    Hatakeyama, Shingo
    Hosogoe, Shogo
    Tanaka, Toshikazu
    Hamano, Itsuto
    Kusaka, Ayumu
    Iwamura, Hiromich
    Fujita, Naoki
    Yamamoto, Hayato
    Tobisawa, Yuki
    Yoneyama, Tohru
    Yoneyama, Takahiro
    Hashimoto, Yasuhiro
    Koie, Takuya
    Ohyama, Chikara
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2018, 23 (01) : 134 - 141
  • [27] Presurgical axitinib therapy increases fibrotic reactions within tumor thrombus in renal cell carcinoma with thrombus extending to the inferior vena cava
    Yoshimi Tanaka
    Shingo Hatakeyama
    Shogo Hosogoe
    Toshikazu Tanaka
    Itsuto Hamano
    Ayumu Kusaka
    Hiromich Iwamura
    Naoki Fujita
    Hayato Yamamoto
    Yuki Tobisawa
    Tohru Yoneyama
    Takahiro Yoneyama
    Yasuhiro Hashimoto
    Takuya Koie
    Chikara Ohyama
    International Journal of Clinical Oncology, 2018, 23 : 134 - 141
  • [28] Neoadjuvant pembrolizumab (PEMBRO) and axitinib (AXI) in renal cell carcinoma with associated inferior vena cava tumor thrombus (NEOPAX).
    Lakritz, Stephanie
    Candelario, Nellowe
    Nicklawsky, Andrew
    Kim, Simon P.
    Kessler, Elizabeth R.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (4_SUPPL) : TPS488 - TPS488
  • [29] Inferior vena cava tumour thrombus and renal cell carcinoma
    Barbara, David W.
    Broski, Stephen M.
    Leibovich, Bradley C.
    Mauermann, William J.
    CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2018, 65 (05): : 588 - 589
  • [30] Inferior vena cava tumour thrombus and renal cell carcinoma
    David W. Barbara
    Stephen M. Broski
    Bradley C. Leibovich
    William J. Mauermann
    Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2018, 65 : 588 - 589