Diagnostic and progression biomarkers in cerebrospinal fluid of Alzheimer's disease patients

被引：0
|
作者：
Chatanaka, Miyo K. [1 ]
Prassas, Ioannis [2 ]
Diamandis, Eleftherios P. [3 ]
机构：
[1] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[2] Univ Hlth Network, Lab Med Program, Toronto, ON, Canada
[3] Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON, Canada
来源：
BMC MEDICINE | 2024年 / 22卷 / 01期
关键词：
Alzheimer's disease; Biomarker; Non-invasive; SMOC1; Neuropentraxin; Diagnostic test; Reference range;
D O I：
10.1186/s12916-024-03270-w
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this commentary, we address a paper published by Johnson et al. by assessing the robustness of their method to discover diagnostic biomarkers in Alzheimer's disease (AD). In addition, we examine how these newly discovered and previously discovered biomarkers, can play a role in assisting patients with AD and those at risk for developing AD, with an emphasis on the translational hurdles that accompany such discoveries.
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页数：4
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