Visible-light-induced synthesis of 2,4-disubstituted quinolines from o-vinylaryl isocyanides and oxime esters

被引：4
|
作者：
Liu, Yu [1 ]
Ding, Chuan [1 ]
Huang, Jia-Jing [1 ]
Zhou, Quan [1 ]
Xiong, Bi-Quan [1 ]
Tang, Ke-Wen [1 ]
Huang, Peng-Fei [1 ]
机构：
[1] Hunan Inst Sci & Technol, Dept Chem & Chem Engn, Yueyang 414006, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 07期
基金：
中国国家自然科学基金;
关键词：
MULTICOMPONENT REACTIONS; CASCADE;
D O I：
10.1039/d3ob02060f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A visible-light-induced radical cyclization reaction of o-vinylaryl isocyanides and oxime esters to access various 2,4-disubstituted quinolines was disclosed. Oxime esters were employed as acyl radical precursors via the carbon-carbon bond cleavage. It provided an effective way for the synthesis of 2-acyl-4-arlysubstituted quinolines under mild conditions and exhibited good functional group tolerance and substrate applicability.
引用
收藏
页码：1458 / 1465
页数：8
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