Biodegradable polyphosphazene - hydroxyapatite composites for bone tissue engineering

被引：11

作者：

Subash, Alsha ^{[1
]}

Basanth, Abina ^{[2
]}

Kandasubramanian, Balasubramanian ^{[1
]}

机构：

[1] Minist Def, Def Inst Adv Technol DU, Nano Surface Texturing Lab, Dept Met & Mat Engn, Pune, Maharashtra, India

[2] CIPET Inst Plast Technol IPT, Biopolymer Sci, Kochi, Kerala, India

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2023年 / 72卷 / 14期

关键词：

Biodegradability; bone tissue engineering (BTE); polyphosphazene; polyphosphazene-hydroxyapatite composite; LIVING CATIONIC-POLYMERIZATION; AMBIENT-TEMPERATURE POLYMERIZATION; LACTIC-ACID ESTER; MECHANICAL-PROPERTIES; IN-VITRO; NANOCRYSTALLINE HYDROXYAPATITE; PHYSICOCHEMICAL PROPERTIES; NANOSIZED HYDROXYAPATITE; BIOMEDICAL APPLICATIONS; MICROSPHERE SCAFFOLDS;

D O I：

10.1080/00914037.2022.2082426

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

The venture to fabricate potential and functional bone regeneration, annihilating the health complexities in conventional bone grafting, made Bone tissue engineering (BTE), which facilitates meticulous control of the spatial and temporal dissemination of cells and extracellular matrix (ECM), receive incredible consideration in the past few years. Ascribable to their exceptional properties, polymers have gotten significant attention as one of the prominent classes of biomaterials for BTE. The compatible mechanical properties, biocompatibility, bioactivity, and biodegradability of polyphosphazene/hydroxyapatite composite made them candidates for functional bone regeneration. This review demonstrates the synthesis, properties, and application of polyphosphazenes, hydroxyapatite, and composite biomaterial for BTE.

引用

页码：1093 / 1111

页数：19

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