Unmasking bipolarity in recurrent depressive disorder following herpes simplex virus triggered n-methyl-D-aspartate encephalitis

被引：7

作者：

Narasimhappa, Karthik ^{[1
]}

Mamtani, Harkishan ^{[1
]}

Jain, Kshiteeja ^{[2
]}

Holla, Vikram V. ^{[2
]}

Ganjekar, Sundarnag ^{[1
]}

Manjunath, Netravathi ^{[2
]}

Kulanthaivelu, Karthik ^{[3
]}

Desai, Geetha ^{[1
]}

机构：

[1] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Psychiat, Hosur Rd, Bangalore 560029, India

[2] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neurol, Bangalore, India

[3] Natl Inst Mental Hlth & Neuro Sci NIMHANS, Dept Neuro Imaging & Intervent Radiol, Bangalore, India

来源：

BIPOLAR DISORDERS | 2024年 / 26卷 / 02期

关键词：

bipolarity; herpes simplex encephalitis; NMDA encephalitis; recurrent depression;

D O I：

10.1111/bdi.13393

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

ObjectiveHerpes simplex virus (HSV) infection triggered n-methyl-D-aspartate (NMDA) encephalitis can lead to varied neuropsychiatric manifestations, including movement disorders and manic symptoms. HSV is known to affect the same brain regions as in secondary mania.MethodWe present a 35-year-old female diagnosed with recurrent depressive disorder (RDD) who developed NMDA encephalitis triggered by HSV infection.ResultHSV-triggered NMDA encephalitis led to a manic switch in a woman with RDD on antidepressants, along with the new onset of dyskinetic movements.ConclusionA neurological insult predisposed our patient to the variable effects of antidepressant drugs.

引用

页码：192 / 195

页数：4

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