The progression of self-powered micro/-nanomotors (MNMs) has rapidly evolved over the past few decades, showing applications in various fields such as nanotechnology, biomedical engineering, microfluidics, environmental science, and energy harvesting. Miniaturized MNMs transduce chemical/biochemical energies into mechanical motion for navigating through complex fluidic environments with directional control via external forces fields such as magnetic, photonic, and electric stimuli. Among various propulsion mechanisms, buoyancy-driven MNMs have received noteworthy recognition due to their simplicity, efficiency, and versatility. Buoyancy force-driven motors harness the principles of density variation-mediated force to overcome fluidic resistance to navigate through complex environments. Restricting the propulsion in one direction helps to control directional movement, making it more efficient in isotropic solutions. The changes in pH, ionic strength, chemical concentration, solute gradients, or the presence of specific molecules can influence the motion of buoyancy-driven MNMs as evidenced by earlier reports. This review aims to provide a fundamental and detailed analysis of the current state-of-the-art in buoyancy-driven MNMs, aiming to inspire further research and innovation in this promising field. This article focuses on a pioneering review of buoyancy-driven micro/-nanomotors (MNMs), providing a comprehensive examination of their propulsion mechanism and applications. The simplicity, cost-effectiveness, precision control, and efficiency of buoyancy-driven MNMs make them highly attractive for multifunctional applications, including biosensing, cargo delivery, and energy generation. For an in-depth understanding, refer to Article No. (202308580) led by Ashish Kumar Shukla and Krishna Kanti Dey.image
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South China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
South China Normal Univ, Sch Mat Sci & Engn, Guangzhou 510640, Guangdong, Peoples R ChinaSouth China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
Dong, Renfeng
Cai, Yuepeng
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South China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R ChinaSouth China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
Cai, Yuepeng
Yang, Yiran
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CALTECH, Div Engn & Appl Sci, Dept Med Engn, Pasadena, CA 91125 USASouth China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
Yang, Yiran
Gao, Wei
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CALTECH, Div Engn & Appl Sci, Dept Med Engn, Pasadena, CA 91125 USASouth China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
Gao, Wei
Ren, Biye
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South China Normal Univ, Sch Mat Sci & Engn, Guangzhou 510640, Guangdong, Peoples R ChinaSouth China Normal Univ, Guangdong Prov Engn Technol Res Ctr Mat Energy Co, Guangzhou Key Lab Mat Energy Convers & Storage, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
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Colorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Mabry, Miles
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Municchi, Federico
Liu, Yiming
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Univ Calif Los Angeles UCLA, Dept Civil & Environm Engn, Calif Nanosyst Inst, Los Angeles, CA USA
Univ Calif Los Angeles UCLA, Inst Environm & Sustainabil, Los Angeles, CA USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Liu, Yiming
Wang, Jingbo
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Univ Calif Los Angeles UCLA, Dept Civil & Environm Engn, Calif Nanosyst Inst, Los Angeles, CA USA
Univ Calif Los Angeles UCLA, Inst Environm & Sustainabil, Los Angeles, CA USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Wang, Jingbo
Cath, Tzahi Y.
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Colorado Sch Mines, Dept Civil & Environm Engn, Golden, CO USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Cath, Tzahi Y.
Turchi, Craig S.
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Natl Renewable Energy Lab, Bldg & Thermal Sci Ctr, Golden, CO USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Turchi, Craig S.
Heeley, Michael B.
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Univ Michigan, Coll Engn, Ctr Entrepreneurship, Ann Arbor, MI USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Heeley, Michael B.
Hoek, Eric M. V.
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Univ Calif Los Angeles UCLA, Dept Civil & Environm Engn, Calif Nanosyst Inst, Los Angeles, CA USA
Univ Calif Los Angeles UCLA, Inst Environm & Sustainabil, Los Angeles, CA USA
Lawrence Berkeley Natl Lab, Energy Storage & Distributed Resources Div, Berkeley, CA USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Hoek, Eric M. V.
Jassby, David
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Univ Calif Los Angeles UCLA, Dept Civil & Environm Engn, Calif Nanosyst Inst, Los Angeles, CA USA
Univ Calif Los Angeles UCLA, Inst Environm & Sustainabil, Los Angeles, CA USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Jassby, David
Martinand, Denis
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Aix Marseille Univ, CNRS, Cent Marseille, M2P2, Marseille, FranceColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA
Martinand, Denis
Tilton, Nils
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Colorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USAColorado Sch Mines, Dept Mech Engn, Golden, CO 80401 USA