Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma

被引：4
|
作者：
Clements, Hollie A. [1 ,2 ]
Underwood, Tim J. [3 ]
Petty, Russell D. [1 ,2 ,4 ,5 ]
机构：
[1] Univ Dundee, Ninewells Hosp, Div Mol & Clin Med, Dundee, Scotland
[2] Univ Dundee, Med Sch, Dundee, Scotland
[3] Univ Southampton, Univ Hosp Southampton NHS Fdn Trust, Sch Canc Sci, Southampton, England
[4] NHS Tayside, Ninewells Hosp, Tayside Canc Ctr, Dundee, Scotland
[5] NHS Tayside, Med Sch, Dundee, Scotland
来源：
BRITISH JOURNAL OF CANCER | 2024年 / 130卷 / 01期
关键词：
ADVANCED RECTAL-CANCER; PEMBROLIZUMAB PLUS CHEMOTHERAPY; LOCALLY ADVANCED ESOPHAGEAL; PHASE-III TRIAL; PREOPERATIVE CHEMOTHERAPY; ADJUVANT CHEMOTHERAPY; OPEN-LABEL; GASTRIC-CANCER; PERIOPERATIVE CHEMOTHERAPY; IMPROVED SURVIVAL;
D O I：
10.1038/s41416-023-02458-w
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Adenocarcinoma of the oesophagus and gastro-oesophageal junction represent a large burden of cancer death in the Western World with an increasing incidence. In the past two decades, the overall survival of patients on a potentially curative treatment pathway has more than doubled due to the addition of perioperative oncological therapies to surgery. However, patients often fail to respond to oncological treatment or struggle to complete their treatment after surgery. In this review, we discuss the current evidence for total neoadjuvant therapy and options for assessment of treatment response.
引用
收藏
页码：9 / 18
页数：10
相关论文
共 50 条
  • [31] Gastro-oesophageal reflux
    Karthik, SV
    JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 2004, 97 (01) : 49 - 49
  • [32] Adenocarcinoma of the gastro-oesophageal junction with a synchronous carcinoid of the duodenum
    McCabe, HL
    POSTGRADUATE MEDICAL JOURNAL, 2001, 77 (906) : 255 - 256
  • [33] Improving individualised therapies in localised gastro-oesophageal adenocarcinoma
    Svrcek, Magali
    Voron, Thibault
    Andre, Thierry
    Smyth, Elizabeth C.
    de la Fouchardiere, Christelle
    LANCET ONCOLOGY, 2024, 25 (09): : e452 - e463
  • [34] Aetiology and classification of adenocarcinoma of the gastro-oesophageal junction/cardia
    McColl, Kenneth E. L.
    Going, James J.
    GUT, 2010, 59 (03) : 282 - 284
  • [35] Maintenance therapy in gastro-oesophageal reflux disease
    Bixquert, M
    DRUGS, 2005, 65 : 59 - 66
  • [36] Maintenance therapy in gastro-oesophageal reflux disease
    Bixquert M.
    Drugs, 2005, 65 (Suppl 1) : 59 - 66
  • [37] Survival Outcomes for Peri-operative chemotherapy for Oesophageal and Gastro-Oesophageal Junction adenocarcinoma
    Goody, R.
    McManus, D.
    Kennedy, R.
    Eatock, M.
    Turkington, R. C.
    BRITISH JOURNAL OF SURGERY, 2016, 103 : 144 - 144
  • [38] Surgical therapy of gastro-oesophageal reflux disease
    Lundell, Lars
    BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2010, 24 (06) : 947 - 959
  • [39] THE INFLUENCE OF SYMPTOMS OF GASTRO-OESOPHAGEAL REFLUX IN THE DEVELOPMENT OF OESOPHAGEAL ADENOCARCINOMA: RESULTS FROM MOSES (MIDLANDS OESOPHAGEAL ADENOCARCINOMA EPIDEMIOLOGY STUDY)
    Cooper, S. C.
    Prew, S.
    Podmore, L.
    Nightingale, P.
    Trudgill, N. J.
    GUT, 2009, 58 : A144 - A144
  • [40] THE RELEVANCE OF THE SIEWERT CLASSIFICATION IN THE ERA OF MULTIMODAL THERAPY FOR ADENOCARCINOMA OF THE GASTRO-OESOPHAGEAL JUNCTION
    Noble, F.
    Bailey, I. S.
    Kelly, J. J.
    Byrne, J. P.
    Underwood, T. J.
    GUT, 2012, 61 : A313 - A313
12345