Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery

In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. Three-dimensional (3D) printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D- printed scaffolds of nanostructured made of graphene oxide and poly-caprolactone (PCL) nanocomposites, which can be magnetically controlled to target cancer cells. The use of graphene oxide in the nanocomposite reinforces the mechanical properties of the scaffolds and improves their biocompatibility. The 3D printing technique used in this study utilizes the 3D-Bioplotter system and NetFab software to translate computer-aided designs into G code that can be printed on the scaffold. The resulting scaffold exhibits high mechanical strength, biodegradability, and controlled drug release capabilities, which make it a promising candidate for targeted cancer therapy. Overall, the innovative 3D-printed scaffolds presented in this study show great potential for improving the efficiency and effectiveness of cancer treatment.