Autologous Gastrointestinal Graft-vs-Host Disease in a Patient With Multiple Myeloma and Hematopoietic Stem Cell Transplantation

被引:0
|
作者
Raza, Hasan [1 ]
Naffouj, Sandra [2 ]
Guzman, Grace [3 ]
Shuja, Asim [2 ]
机构
[1] Univ Illinois, Dept Med, Chicago, IL 60607 USA
[2] Univ Illinois, Dept Med, Div Gastroenterol & Hepatol, Chicago, IL USA
[3] Univ Illinois, Dept Pathol, Chicago, IL USA
关键词
colitis; graft-vs-host disease; autologous; stem cell transplant; gastrointestinal tract; RECIPIENTS; TRACT;
D O I
10.14309/crj.0000000000001281
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Graft-vs-host disease (GVHD) of the gastrointestinal (GI) tract is notably a serious complication of allogeneic hematopoietic stem cell transplant (HSCT). However, GI GVHD has rarely been reported in autologous HSCT, and the pathophysiology remains unclear. Diagnosing GVHD after autologous HSCT requires a high level of clinical suspicion, given its nonspecific clinical presentation and endoscopic findings necessitating a histological diagnosis for confirmation. We present a case of autologous GVHD involving the GI tract in a patient with multiple myeloma who responded well to corticosteroids, highlighting the importance of early identification of this rare entity to initiate therapy and improve outcomes.
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页数:3
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