Regulation of Alternative Splicing in B-Cell ALL By DYRK1A

被引:0
|
作者
Jin, Qi [1 ]
Harris, Ethan [1 ]
Myers, Jacquelyn A. [2 ]
Cotton, Anitria [3 ]
Wen, Jeremy [3 ]
Melo-Cardenas, Johanna [1 ]
Yoshimi, Akihide [4 ]
Abdel-Wahab, Omar [5 ]
Obeng, Esther A. [2 ]
Crispino, John D. [3 ]
机构
[1] St Jude Childrens Res Hosp, Memphis, TN USA
[2] St Jude Childrens Res Hosp, Oncol, Memphis, TN USA
[3] St Jude Childrens Res Hosp, Div Expt Hematol, Memphis, TN USA
[4] Natl Canc Ctr, Tokyo, Japan
[5] Mem Sloan Kettering Canc Ctr, New York, NY USA
关键词
D O I
10.1182/blood-2023-174923
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [31] Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation
    Kaltheuner, Ines H.
    Anand, Kanchan
    Moecking, Jonas
    Duester, Robert
    Wang, Jinhua
    Gray, Nathanael S.
    Geyer, Matthias
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [32] CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition
    Abdolazimi, Yassan
    Zhao, Zhengshan
    Lee, Sooyeon
    Xu, Haixia
    Allegretti, Paul
    Horton, Timothy M.
    Yeh, Benjamin
    Moeller, Hannah P.
    Nichols, Robert J.
    McCutcheon, David
    Shalizi, Aryaman
    Smith, Mark
    Armstrong, Neali A.
    Annes, Justin P.
    ENDOCRINOLOGY, 2018, 159 (09) : 3143 - 3157
  • [33] B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation
    Liat Stoler-Barak
    Ethan Harris
    Ayelet Peres
    Hadas Hezroni
    Mirela Kuka
    Pietro Di Lucia
    Amalie Grenov
    Neta Gurwicz
    Meital Kupervaser
    Bon Ham Yip
    Matteo Iannacone
    Gur Yaari
    John D. Crispino
    Ziv Shulman
    Nature Communications, 14
  • [34] DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B
    Yousefelahiyeh, Mina
    Xu, Jingyi
    Alvarado, Estibaliz
    Yu, Yang
    Salven, David
    Nissen, Robert M.
    PLOS ONE, 2018, 13 (11):
  • [35] B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation
    Stoler-Barak, Liat
    Harris, Ethan
    Peres, Ayelet
    Hezroni, Hadas
    Kuka, Mirela
    Di Lucia, Pietro
    Grenov, Amalie
    Gurwicz, Neta
    Kupervaser, Meital
    Yip, Bon Ham
    Iannacone, Matteo
    Yaari, Gur
    Crispino, John D.
    Shulman, Ziv
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [36] Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B
    Walmsley, David Lee
    Murray, James B.
    Dokurno, Pawel
    Massey, Andrew J.
    Benwell, Karen
    Fiumana, Andrea
    Foloppe, Nicolas
    Ray, Stuart
    Smith, Julia
    Surgenor, Allan E.
    Edmonds, Thomas
    Demarles, Didier
    Burbridge, Mike
    Cruzalegui, Francisco
    Kotschy, Andras
    Hubbard, Roderick E.
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (13) : 8971 - 8991
  • [37] A natural DYRK1A inhibitor as a potential stimulator for β-cell proliferation in diabetes
    Zheng, Mengzhu
    Zhang, Qingzhe
    Zhang, Chengliang
    Wu, Canrong
    Yang, Kaiyin
    Song, Zhuorui
    Wang, Qiqi
    Li, Chen
    Zhou, Yirong
    Chen, Jiachun
    Li, Hua
    Chen, Lixia
    CLINICAL AND TRANSLATIONAL MEDICINE, 2021, 11 (07):
  • [38] DYRK1A Kinase Inhibitors Promote β-Cell Survival and Insulin Homeostasis
    Barzowska, Agata
    Pucelik, Barbara
    Pustelny, Katarzyna
    Matsuda, Alex
    Martyniak, Alicja
    Stepniewski, Jacek
    Maksymiuk, Anna
    Dawidowski, Maciej
    Rothweiler, Ulli
    Dulak, Jozef
    Dubin, Grzegorz
    Czarna, Anna
    CELLS, 2021, 10 (09)
  • [39] Regulation of RCAN1 Protein Activity by Dyrk1A Protein-mediated Phosphorylation
    Jung, Min-Su
    Park, Jung-Hwa
    Ryu, Young Shin
    Choi, Sun-Hee
    Yoon, Song-Hee
    Kwen, Mi-Yang
    Oh, Ji Youn
    Song, Woo-Joo
    Chung, Sul-Hee
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (46) : 40401 - 40412
  • [40] Imbalance in Alternative Splicing of MCL-1 Inhibits Apoptosis in Diffuse Large B-Cell Lymphoma
    Rekers, Nicolle H.
    Moesbergen, Laura M.
    Hijmering, Nathalie J.
    Vos, Wim
    Oudejans, Joost
    Ossenkoppele, Gert J.
    Meijer, Chris J. L. M.
    Cillessen, Saskia A. G. M.
    BLOOD, 2014, 124 (21)